Actinamide Injection 1000 Micrograms (Cobamamide Injection)

Adult dosage

Adults: Administer 0.5 to 1 mg of cobamamide by intramuscular injection. Adjust according to age and symptoms.

Because this drug is an ampoule injection, glass fragments may mix when cutting the container, so care must be taken to avoid mixing glass fragments during use. Particular caution is required when used in children and the elderly. This drug should not be used in individuals allergic to its ingredients or in children under 7 years of age. Patients receiving medical treatment or taking other medications, pregnant or breastfeeding women, and patients experiencing persistent diarrhea or bloody stools accompanied by fever should use this drug cautiously. Allergic reactions may cause skin rashes, and mild diarrhea or itching may temporarily occur. When there is vitamin B12 deficiency, other vitamin deficiencies may also be present; therefore, multiple vitamin deficiencies must be considered, and the presence of vitamin B12 deficiency must be confirmed before administration. For patients with folate deficiency, care should be taken as blood-related side effects may occur with doses above a certain threshold. If anemia symptoms do not improve after administration, the possibility of folate metabolism disorders should be considered, and regular blood tests are essential. If absorption is poor when orally administered, it is preferable to administer the injection form. Long-term use for more than a week should be avoided, and if no effect is observed, it is advisable not to use it for more than a month. This drug may interact with certain antibiotics, methotrexate, and pyrimethamine, and chloramphenicol may reduce the effectiveness of this drug. Additionally, prolonged use of H2 receptor antagonists can lead to vitamin B12 deficiency, so caution is advised. Pregnant women should only use this drug if macrocytic anemia due to vitamin B12 deficiency is confirmed. This drug should be kept out of reach of children, and since the ingredients may decompose when exposed to light, it should be stored in a place avoiding direct sunlight and at room temperature. Moreover, do not transfer it to another container, and be sure to store it closed in its original container to prevent quality degradation or misuse.

Mild side effects

• Rashes may occur as an allergic reaction.
• Mild, temporary diarrhea and itching.

This drug should be stored in a sealed container that can block light, and it is recommended to store it at room temperature. This way, the drug's ingredients will not change and will maintain their effectiveness.

Appearance

It is a brown ampoule injection containing a red liquid.

Package unit

2 milliliters/ampoule x 10