Samion Tablet (Nisergoline)

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 3 times daily before meals. The dose may be adjusted as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before meals. If the desired effect is not achieved at this dose, it may be increased to 60 mg. The dose may be reduced after symptoms improve. For patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

This medication should not be used in certain patients. For instance, it should not be administered to individuals allergic to this drug or ergot alkaloids, those with acute myocardial infarction or acute hemorrhage, those taking sympathomimetic drugs, individuals with very slow heart rates, patients who have not achieved hemostasis after intracranial bleeding, and those with orthostatic disorders. Caution should be exercised when using this medication in patients with mild bradycardia or impaired renal function. Additionally, this medication contains the dye known as Yellow No. 5, so individuals with allergies or hypersensitivity to this component should also be careful. While rare, gastrointestinal symptoms such as loss of appetite, diarrhea, constipation, nausea, vomiting, and side effects like liver function abnormalities, dizziness, blood pressure changes, drowsiness, headaches, and rashes may occur. It is advisable to consult healthcare professionals if these symptoms occur. When used in conjunction with antihypertensive medications, blood pressure may drop too low, so blood pressure should be monitored frequently. Furthermore, this medication can affect uric acid levels, so patients with gout or hyperuricemia should be particularly cautious. After taking this medication, care should be taken while driving or operating machinery. This medication is metabolized in the liver and may interact with other drugs. Special caution is needed when taken with antihypertensive agents as the effects may be enhanced. Women who are pregnant or may become pregnant should consult a physician before taking this medication, and nursing mothers should either avoid it or discontinue breastfeeding. Elderly patients may have decreased bodily function; therefore, dosage should be reduced or careful attention paid when using this medication. Its safety in children has not been sufficiently established, so it is advisable to avoid use in pediatric patients. In case of overdose, blood pressure may temporarily decrease, so blood pressure changes should be monitored closely, and appropriate action should be taken as needed. Finally, this medication should be stored out of the reach of children and kept sealed in its original container for safety.

• Loss of appetite
• diarrhea
• constipation
• nausea
• vomiting
• sporadic upper abdominal pain
• cramps
• thirst
• ALT elevation
• AST elevation

This medication should be stored in a sealed container that blocks light and should be kept at room temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness and prevent deterioration.

Appearance

This tablet is an orange coated tablet.

Package unit

For domestic use (30 tablets) - 30 tablets/bottle, For domestic use (100 tablets) - 100 tablets/bottle