Hwanin Hidantoin Tablet (Phenytoin)

Key information summary

Efficacy & effects

This drug is primarily used to treat tonic-clonic seizures (grand mal), partial seizures (focal seizures), and psychomotor seizures in patients with epilepsy. Additionally, in injectable form, it is effectively used for status epilepticus and in cases where oral administration is difficult for seizure suppression, especially when consciousness is impaired or during and after surgery. Furthermore, it helps in treating severe arrhythmias induced by digitalis when first-line treatment is ineffective. This drug is widely used for various types of epileptic seizures and certain arrhythmias.

Dosage

Tablets and capsules: Phenytoin should be orally administered as a single dose of 100 mg three times a day, with a maintenance dose of 300-400 mg divided daily. A maximum of 600 mg can be increased per day. Injectable form: In status epilepticus, sodium phenytoin should be administered slowly by intravenous injection at a dose of 125-250 mg at a rate not exceeding 50 mg/min. If necessary, an additional 100-150 mg can be administered 30 minutes later.

Precautions

This drug is used for the treatment of epilepsy. During treatment, there is a risk of mood changes, such as suicidal thoughts or behavior and depression, so patients and caregivers should closely monitor for these symptoms. In injectable form, inflammation or tissue damage may occur at the injection site, and in severe cases, skin necrosis or pain may arise. Patients with known allergies to this drug or its components, heart problems, or blood disorders should not receive this medication. Caution is needed for patients with impaired liver or kidney function, heart disease, diabetes, and hypothyroidism, and they should consult a doctor immediately if skin rashes or abnormal symptoms appear. Mental side effects such as dizziness, movement disorders, and insomnia may occur, and in severe cases, neurological symptoms may develop, necessitating caution. This drug can affect multiple organs, including the liver, blood, skin, kidneys, and eyes, so regular examinations are necessary. It also has a high potential for interactions with other medications, so patients must inform healthcare providers about all the medications they are taking. During pregnancy, there is a risk of congenital malformations or developmental disorders in the fetus, so women planning to become pregnant must consult before taking this drug, and administration during pregnancy should be avoided if possible. In elderly patients, side effects may be more pronounced due to reduced bodily functions; therefore, starting with a low dose and tapering off slowly is advised. Overdose may lead to central nervous system symptoms and respiratory or blood pressure drop, requiring immediate emergency treatment. This drug should be kept out of reach of children, and it is advisable not to transfer it to other containers. Finally, during treatment, drowsiness or decreased concentration may occur, so activities such as driving or operating dangerous machinery should be avoided.

Side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, cough with fever and respiratory abnormalities, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urinary issues

Alternatives / Same-ingredient medications

• 

  Buhwang Phenytoin Capsule 100 mg

  Same ingredient
• 

  Myungin Phenytoin Tablet 100mg

  Same ingredient

Related searches