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Key information summary
Efficacy & effects
Improvement of arthritis in rheumatoid arthritis and osteoarthritis
Adult dosage
1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis
For adults, naproxen is administered orally at a dose of 250-500 mg twice a day (every 12 hours).
2. Acute Gout
For adults, an initial dose of 750 mg of naproxen is administered orally, followed by 250 mg every 8 hours until the attack subsides.
3. Skeletal muscle disorders, postoperative pain, post-extraction pain, dysmenorrhea, tendinitis, bursitis
For adults, naproxen
Ingredients
Naproxen
Rx / OTC
OTC medication
Appearance
Light yellow (pale yellow) oval tablet
Efficacy & effects
This medication is effective for rheumatoid arthritis, osteoarthritis (degenerative joint disease), ankylosing spondylitis, tendinitis (tendonitis), acute gout, and dysmenorrhea. It is also used for bursitis and skeletal muscle disorders (sprains, strains, trauma), low back pain, postoperative pain, migraine, and post-extraction pain. It helps relieve pain and reduce inflammation in these conditions and symptoms, improving patients' quality of life. Therefore, this medication is useful in treating various joint and muscle-related disorders and pain symptoms.
Dosage
1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis For adults, naproxen is administered orally at a dose of 250-500 mg twice a day (every 12 hours). 2. Acute Gout For adults, an initial dose of 750 mg of naproxen is administered orally, followed by 250 mg every 8 hours until the attack subsides. 3. Skeletal muscle disorders, postoperative pain, post-extraction pain, dysmenorrhea, tendinitis, bursitis For adults, naproxen
Precautions
Patients who regularly consume more than three glasses of alcohol daily must consult a physician or pharmacist before taking this medication. Taking it with alcohol may increase the risk of gastrointestinal bleeding. This medication can increase the risk of cardiovascular disease. It may cause serious vascular problems such as heart attacks or strokes, so patients with cardiovascular conditions or risk factors should be especially cautious. Symptoms related to cardiovascular issues should be carefully monitored during use, and if symptoms develop, immediate consultation with healthcare providers is necessary. This medication can cause serious gastrointestinal issues such as gastrointestinal bleeding, ulcers, and perforation. Elderly patients or those who take it for extended periods may have an increased risk, so any gastrointestinal symptoms should prompt immediate medical attention. Patients with peptic ulcers, severe liver impairment, kidney failure, hypertension, or severe heart failure should not take this medication. Additionally, individuals allergic to the components of this drug or similar medications should avoid its use. Allergic reactions such as hypersensitivity, difficulty breathing, hypotension, skin rashes may occur rarely; if such symptoms appear, discontinue use immediately and consult medical personnel. This medication may affect liver and kidney function, so patients with liver or kidney diseases must consult healthcare professionals before taking it, and regular checkups are necessary during treatment. This medication should particularly be avoided during late pregnancy, and women who might become pregnant should consult a physician before use. Nursing mothers are also advised against taking this medication. Children under 2 years of age should not be administered this drug unless necessary, and for older children, it should be administered with caution at the minimum effective dosage. Elderly patients are at higher risk of side effects such as gastrointestinal bleeding, so initial dosing should be at the minimum, and they should be monitored carefully for any adverse reactions. This medication may interact with other nonsteroidal anti-inflammatory drugs, certain antiepileptics, blood pressure medications, diuretics, anticoagulants, etc., so if other medications are being taken, it is essential to inform healthcare providers. In case of overdose, symptoms such as drowsiness, indigestion, vomiting may occur, and immediate medical treatment is required.
Side effects
Hives, severe swelling (edema), cold sweats, swelling (edema), difficulty breathing, anaphylactic reactions, hematemesis, gastrointestinal bleeding, peptic ulcers, perforation, jaundice, hepatitis, kidney impairment, renal failure, severe headaches, altered consciousness, aseptic meningitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, severe skin adverse reactions, impaired platelet function, blood disorders (agranulocytosis, leukopenia, thrombocytopenia, aplastic anemia, hemolytic anemia), severe
Interactions
Do not take this medication with other nonsteroidal anti-inflammatory drugs, aspirin, or high doses of methotrexate. It should not be taken with hydantoin antiepileptics, sulfonamides, sulfonylureas for lowering blood sugar, propranolol and other beta-blockers, ACE inhibitors, loop diuretics, thiazide diuretics, probenecid, lithium, low-dose methotrexate, coumarin anticoagulants, zidovudine, or quinolone antibiotics.
