Ampsillin Capsule 250 mg (Ampicillin Trihydrate)

Adult dosage

(Capsules)(Dry syrup) ○ Adults: Administer 250～500mg (potency) of ampicillin orally per dose, 4～6 times daily. ○ In cases of sepsis or bacterial endocarditis, use a higher dose than the usual dose. Adjust the dose as appropriate according to age and symptoms. (Injection) 1. Intramuscular injection ○ Adults: Inject 250～1000mg (potency) of ampicillin intramuscularly per dose, 2～4 times daily. 2. Intravenous injection ○ Adults: For severe infections, dissolve 1～2g (potency) daily of ampicillin in 20mL of 5% dextrose injection or normal saline injection and administer intravenously in 1～2 divided doses. For intravenous infusion, dissolve 1～2g (potency) daily in 500mL of an electrolyte solution or 5% dextrose injection and administer in 1～2 divided doses. In cases of sepsis or bacterial endocarditis, use a higher dose than the usual dose. Adjust the dose as appropriate according to age and symptoms.

Children's dosage

○ Children: Administer 25～50mg (potency) per kg of body weight daily in 4 divided oral doses (dry syrup only).

This medication should not be used in certain patients. For instance, it is dangerous to administer it to individuals who have experienced severe allergic reactions or shock from this medication, or who have allergies or hypersensitivity history to penicillins or cephalosporin antibiotics. Patients with infectious mononucleosis or genetic issues such as lactose intolerance, lactose deficiency, or glucose-galactose malabsorption should also avoid taking this medication. Caution is warranted when administering this medication to patients with allergic tendencies, severe kidney impairment, those who have difficulty with oral intake, and elderly patients. Especially, signs of vitamin K deficiency may occur, so their condition should be monitored closely. This medication contains a dye called Yellow No. 5, and patients allergic to this ingredient or with a history of hypersensitivity should use it cautiously. During administration, if symptoms of allergy such as shock, fever, rash, hives, severe abdominal pain, diarrhea, or blood in stools occur, the medication should be stopped immediately and medical consultation sought. Rarely, blood disorders, central nervous system symptoms, skin diseases, liver dysfunction, and kidney impairment may occur, so regular tests are necessary. Additionally, prolonged or excessive use of this medication may increase the risk of bleeding due to vitamin K deficiency, so caution is advised. To prevent the development of drug-resistant bacteria, it is recommended to perform susceptibility testing and to administer only for the minimum necessary duration. Prior to use, check for allergic reactions, and closely observe the patient's stable condition after administration. This medication should be preferred in oral form when oral administration is possible, and injectable form should only be used when oral administration is not feasible. This medication may decrease the effectiveness of oral contraceptives, so additional contraceptive methods are recommended to enhance contraceptive efficacy. Moreover, interactions with other medications may occur, so it is essential to inform the healthcare provider about any concurrent medications being taken. During pregnancy, the safety is not established; it should only be administered when the therapeutic benefit outweighs the risks, and it is advisable to discontinue breastfeeding while on this medication. Elderly patients are at increased risk of side effects due to declining bodily functions, so dosages and administration intervals should be adjusted carefully. Finally, this medication may cause false-positive results in urine glucose tests, so caution is advised during testing. When using injectable forms, care should be taken with the injection site and method to prevent side effects such as phlebitis.

shock

This medication must be stored in a tightly closed container to avoid exposure to air and moisture. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature to preserve the medication’s efficacy.

Appearance

The capsule contains a white or pale yellow crystalline powder; the cap is red and the body is a cloudy purple.

Package unit

500 capsules/bottle