Daehan Ascorbic Acid Injection

Key information summary

Efficacy & effects

This medication is used for the prevention and treatment of scurvy, which is a vitamin C deficiency. It also helps in cases of increased vitamin C requirements during pregnancy, breastfeeding, or intense physical labor. It is effective in promoting capillary hemorrhages, metabolic disorders due to drug administration, and enhancing bone matrix formation and bone healing in fractures. This medication is also used to improve skin issues such as melasma, freckles, post-inflammatory hyperpigmentation, and photosensitive dermatitis. It effectively acts in various conditions related to vitamin C deficiency.

Dosage

As ascorbic acid, administer 50-1,000 mg once daily or in divided doses via subcutaneous, intramuscular, or intravenous injection. Adjust dosage appropriately according to age and symptoms.

Precautions

This medication is administered via injection and requires careful cutting of the glass container before use since glass fragments could mix with the injection solution, causing adverse reactions. Special caution is advised when used in children or the elderly. This medication should not be administered to certain patients. For example, individuals with allergies to this drug or its components, patients with hyperoxaluria or thalassemia, patients with gout or cystinuria, and those with G6PD deficiency should avoid its use. Additionally, individuals with kidney stones should not exceed a dosage of 1 gram per day. Since it contains sodium bisulfite, which can cause allergic reactions, particular caution is needed for asthmatic patients. Severe asthma attacks can occur in some patients. Possible side effects include nausea, vomiting, diarrhea, heartburn, abdominal cramps, fatigue, facial flushing, headache, and insomnia. Exceeding 1 gram per day can increase the risk of diarrhea and kidney stones, and doses greater than 600 milligrams may cause diuretic effects. Patients with G6PD deficiency should be cautious due to the risk of hemolysis. Excessive intake of ascorbic acid may cause precipitation of oxalate or other substances in the urinary tract, so caution is advised. This medication is generally administered orally but should only be used for injection in acute situations or when oral administration is not possible. Transitioning to oral administration should be done quickly when possible. This medication may interact with other drugs. Salicylates can interfere with its absorption, and caution is warranted when used with aspirin, nicotine, alcohol, certain appetite suppressants, iron preparations, anticonvulsants, oral contraceptives, and tetracycline antibiotics due to potential side effects. Additionally, high-dose use may reduce the effects of oral anticoagulants. Interactions may also occur with certain psychiatric medications, so consultation with a specialist is necessary when combining therapies. The safety of this medication during pregnancy has not been fully established, so it should be used only when the benefits outweigh the risks. Caution should be exercised particularly with high-dose administration exceeding 1 gram, as it poses a risk of inducing scurvy in newborns. Although this medication is passed into breast milk, there have been no significant risks reported to infants at standard doses. This medication may affect the results of some clinical tests. For instance, it may cause false-negative reactions in urine tests for glucose or blood tests, so this should be kept in mind during testing. Overdosage may increase the risk of diarrhea and kidney stones and may cause diuretic effects. If overdose symptoms occur, administration should be stopped immediately, and appropriate treatment should be sought. Injection may cause temporary pain at the injection site. For subcutaneous or intramuscular injections, only the minimum necessary dose should be used, and care should be taken not to repeat injections in the same area. Extra caution is necessary when injecting newborns or children. If severe pain or blood reflux is observed during needle insertion, the needle should be removed immediately. Intravenous injections should be administered slowly to prevent dizziness or vessel pain. Finally, this medication should be stored out of reach of children, away from direct sunlight, and in a dry place. It should not be transferred from its original container to another container, and it should be securely sealed for storage.

Side effects

Severe allergic reactions such as sulfite anaphylaxis, asthma attacks, hemolysis, kidney stones, increased risk of diarrhea and kidney stones

Alternatives / Same-ingredient medications

• Cheil Pharmaceutical Ascorbic Acid Injection 5%

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• Dae Won Ascorbic Acid Injection 500mg

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• Chereul Pharmaceutical Ascorbic Acid Injection 500 Milligrams

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• Huons Ascorbic Acid Injection

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