Ingredient

Simvastatin

Simvastatin is an ingredient that lowers blood cholesterol and prevents atherosclerosis.

See medicines used for Chronic Conditions
All medicines
177
Single ingredient
76
Combination
101
Prescription medication
177

MFDS ingredient code M089710

What does it do?

Simvastatin is a lipid-lowering agent of the statin class, primarily used in the treatment of hypercholesterolemia. This ingredient works by inhibiting cholesterol synthesis in the liver, thereby reducing blood LDL cholesterol levels.

Simvastatin reduces cholesterol production by blocking the enzyme that creates cholesterol in the liver. As a result, the levels of bad cholesterol (LDL) in the blood decrease, which helps prevent plaque formation in the arteries and supports vascular health.

Commonly used for

Approved uses differ by product. Check each product's information for its actual use.

Good to know

Simvastatin is similar to other statin drugs but has the characteristic of being converted to its active form in the liver. Additionally, it is lipophilic, allowing it to penetrate tissues effectively, demonstrating effects in various tissues.

Medicines containing this ingredient

Even with the same ingredient, strength, dosage form and how it is taken can differ.

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177 total

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Even with the same ingredient, dosage and approved uses can differ by strength, dosage form and combined ingredients. Check each product's information before taking it.

Combined ingredients

Ingredients used together with this ingredient in combination products.

Questions about this ingredient

  • QMy mother is taking a statin and has also received another cholesterol medication.

    There are several products in the statin class, and the active ingredients can overlap. Make sure to bring both the newly received medication and your existing medications to show your pharmacist or the prescribing physician to confirm they can be taken together.

    Answers 1 · 2026.09.14

  • QMy levels have improved, can I stop taking it now?

    Simvastatin is a medication that manages cholesterol levels by inhibiting cholesterol production, so an improvement in your levels may indicate the effectiveness of the medication. Please do not stop or reduce the dosage on your own; consult with the prescribing doctor.

    Answers 1 · 2026.09.14

  • QHow does Simvastatin lower cholesterol?

    Simvastatin blocks the enzyme that produces cholesterol in the liver, thereby reducing the amount of cholesterol generated. As a result, it is explained that LDL cholesterol in the blood decreases and the formation of plaque in the arteries is inhibited.

    Answers 1 · 2026.09.14

For anything that needs medical judgment, consult a doctor or pharmacist.

SourceKorea Ministry of Food and Drug Safety (Drug Safety Korea)

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.