Ingredient

Aprepitant

Aprepitant is a medication used to prevent nausea and vomiting caused by chemotherapy.

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Single ingredient
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Prescription medication
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MFDS ingredient code M211076

What does it do?

Aprepitant is a drug that blocks the neuropeptide substance P receptor, neurokinin 1 (NK1), and is primarily used to prevent nausea and vomiting induced by chemotherapy. This component belongs to the class of antiemetics and is included in medications for its efficacy in effectively suppressing nausea and vomiting.

Aprepitant prevents the action of substance P, a neuropeptide that binds to NK1 receptors in the brain and gastrointestinal tract, thereby blocking the signals of nausea and vomiting. This reduces nausea and vomiting during chemotherapy, alleviating the patient's discomfort.

Commonly used for

Approved uses differ by product. Check each product's information for its actual use.

Good to know

Aprepitant is characterized by its targeting of NK1 receptors to prevent nausea and vomiting, unlike existing serotonin receptor antagonists. As a result, it can provide more effective suppression of nausea when used in combination with other antiemetics.

Medicines containing this ingredient

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, dosage and approved uses can differ by strength, dosage form and combined ingredients. Check each product's information before taking it.

Questions about this ingredient

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For anything that needs medical judgment, consult a doctor or pharmacist.

Product approval information is based on drug information provided by the Ministry of Food and Drug Safety.
Ingredient and class descriptions are not part of MFDS data and were written separately by Cashdoc.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.