Medication info
Jepito Tablets 10/5 mg (Ezetimibe, Atorvastatin)

Jepito Tablets 10/5 mg (Ezetimibe, Atorvastatin)

Prescription medicationTablet경구
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›5.425mg / 1 tablet
Manufacturer / importer
에이치케이이노엔(주)
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle, 30 tablets/box [(10 tablets/PTP x 3)]
Approval status
Active

MFDS item code 202503099 · Approved 2025.11.27

Summary

Main use
Improvement of hypercholesterolemia (primary, mixed) and treatment of dyslipidemia
Who takes it
Adults
Adult dose
This medication is administered once daily regardless of meals. For primary hypercholesterolemia, the dosage range is 10/5 mg to 10/80 mg per day. The recommended initial dose is 10/5 mg, 10/10 mg, or 10/20 mg once daily. For patients requiring greater reduction in LDL cholesterol (more than 55%), an initial dose of 10/40 mg once daily is recommended. After starting treatment or adjusting the dose, lipid levels should be checked at intervals of at least 2 weeks.

Ingredients

Manufacturer
에이치케이이노엔(주)

Efficacy & effects

Improvement of hypercholesterolemia (primary, mixed) and treatment of dyslipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • elevated total cholesterol
  • elevated LDL cholesterol
  • elevated apolipoprotein B
  • elevated triglycerides
  • elevated non-HDL cholesterol
View approved original text

This medication helps to lower elevated total cholesterol, LDL cholesterol, apolipoprotein B, triglycerides, and non-HDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia. At the same time, it increases HDL cholesterol levels when used in conjunction with the recommended dietary regimen, contributing to improved cardiovascular health. Thus, this medication plays an important role in effectively controlling blood lipid levels and reducing the risk of cardiovascular diseases. By following your treatment plan with this medication, you can manage your cholesterol levels effectively. This medication is used to regulate and improve healthy blood lipid levels.

How to take

Adult dose

This medication is administered once daily regardless of meals. For primary hypercholesterolemia, the dosage range is 10/5 mg to 10/80 mg per day. The recommended initial dose is 10/5 mg, 10/10 mg, or 10/20 mg once daily. For patients requiring greater reduction in LDL cholesterol (more than 55%), an initial dose of 10/40 mg once daily is recommended. After starting treatment or adjusting the dose, lipid levels should be checked at intervals of at least 2 weeks.

Precautions

This medication can affect muscle tissue and may rarely lead to muscle damage that can cause kidney problems. Therefore, if severe muscle pain or muscle weakness occurs, consult a physician immediately. The use of this medication should be temporarily halted or discontinued in cases of severe infections, hypotension, major surgery, trauma, or metabolic disorders. It should not be used in patients with allergic reactions to specific ingredients, active liver disease, unexplained liver enzyme elevations, or muscle disorders. It should also not be administered to pregnant or potentially pregnant women, or nursing mothers. Caution is required when used in patients with a history of alcohol addiction, poor liver function, kidney problems, hypothyroidism, or elderly patients, as they may be at higher risk for muscle disorders. When used in combination with other medications, the risk of muscle damage may increase, so it is essential to inform your physician about all medications you are taking and be cautious. Regular monitoring of liver function and muscle condition is necessary while taking this medication, and any unusual symptoms should be reported immediately. Additionally, dizziness may occur during driving or operating machinery, so caution is advised. Women of childbearing age should use appropriate contraception while taking this medication and should discontinue it immediately if pregnancy is confirmed. In case of overdose, there is no specific antidote available, so it is important to receive symptomatic and supportive treatment.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucous membranes, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities with cough + fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion in consciousness, visual disturbances, paralysis, urination

Mild side effects

  • Headache
  • dizziness
  • altered sensation
  • fainting
  • nasopharyngitis
  • adenovirus infection
  • cystitis
  • miliaria
  • periodontitis
  • retinitis
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  • dyspepsia
  • constipation
  • colonic polyps
  • aphthous ulcers
  • pruritus
  • dermatitis
  • dry eyes
  • keratitis
  • macular hole
  • ocular congestion
  • vitreous floaters
  • weakness
  • chest pain
  • increased alanine aminotransferase
  • increased aspartate aminotransferase
  • increased alkaline phosphatase
  • increased blood pressure

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is advisable to maintain a storage temperature between 1 to 30 degrees Celsius (room temperature).

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 30 tablets/box [(10 tablets/PTP x 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.