Trubeta Tablet 80/5/12.5 mg (Telmisartan, Amlodipine, Chlorthalidone)

Adult dose

This medication is taken as one tablet once daily with water, regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). For patients whose blood pressure is not controlled with telmisartan/amlodipine combination therapy, this medication can be administered in a dose of 40/5/12.5 mg, and the dosage should be adjusted considering the patient's blood pressure response, at intervals of more than two weeks. The maximum recommended dose of this medication is 80/5/25 mg.

This medication can cause severe harm to the fetus during pregnancy, especially in the second and third trimesters, thus women who are pregnant or may become pregnant should not take it. Patients with impaired liver function or progressive liver disease should be cautious as serious side effects such as hepatic coma may occur with this medication. Patients with severe renal disease should use this medication cautiously as it may worsen kidney function or increase blood nitrogen levels. Patients who are allergic to any of the components of this medication or have hypersensitivity, as well as those with specific heart diseases or obstructive biliary disorders, should not take this medication. Lactating women should also avoid this medication as its components may pass into breast milk and affect the infant. Patients with severely low blood pressure, renal failure, electrolyte imbalances such as hypokalemia, hyponatremia, and hypercalcemia should also exercise caution when taking this medication. In elderly patients, the blood pressure-lowering effect may be excessive, so it's important to start at a low dose and closely monitor their condition. While taking this medication, dizziness or hypotensive symptoms may occur, so care should be taken when driving or operating dangerous machinery. While on this medication, blood pressure, kidney function, and serum electrolyte levels should be regularly monitored for abnormalities. When used in combination with other antihypertensive medications, diuretics, lithium, digoxin, or other drugs, the risk of side effects from interactions may increase, so it is essential to consult a doctor. In the event of overdose, symptoms such as hypotension, dizziness, arrhythmias, and renal failure may occur, and immediate medical attention is required.

Serious side effects

Hives, severe swelling (edema), chest tightness, shortness of breath, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, difficulty breathing or shortness of breath, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme fatigue, sudden and very severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urinary changes

Mild side effects

• Dizziness
• dyslipidemia
• back pain
• rash
• orthostatic dizziness
• headache
• abdominal pain
• rectal bleeding
• nausea
• hemorrhagic gastritis

This medication may be sensitive to light, so it should be stored in a dark place. It is also advisable to keep it at room temperature between 1°C and 30°C to maintain its effectiveness.

Appearance

White oval-shaped bilayer tablet

Package unit

30 tablets/box (10 tablets/PTP×3)