Empavex 12.5/850 mg (Empagliflozin, Metformin Hydrochloride)

Adult dose

The recommended dosage of this medication is 1 tablet per dose, twice a day. The decision should be made considering each patient's treatment regimen, efficacy, and tolerability without exceeding the maximum recommended daily dosage of Empagliflozin 25 mg and Metformin 2000 mg. Patients who have difficulty controlling blood sugar with monotherapy of Metformin or in combination with insulin or other medications are recommended to take 5 mg of Empagliflozin twice a day along with their existing dose of Metformin.

This medication is used for the treatment of diabetes, helping to lower blood sugar. However, severe lactic acidosis, a rare side effect, can occur, necessitating caution. When used in conjunction with other diabetes treatments, there is a risk of hypoglycemia, so care should be taken. Patients with impaired kidney function or acute disease should not use this medication. Additionally, women who are pregnant or breastfeeding should not take this medication. Regular kidney function tests should be performed while taking this medication, and it may be temporarily discontinued during periods of dehydration, severe infection, or before and after surgery. Patients at risk of fluid loss or elderly patients should be especially cautious when using this medication. Side effects such as gastrointestinal disturbances, urinary tract infections, genital infections, increased urination may occur; if symptoms arise, consult a physician. Symptoms of hypoglycemia, where blood sugar levels drop too low, can also appear; it is advisable to eat regularly and avoid sudden exercise or drinking alcohol. This medication should be used cautiously in patients with liver dysfunction, as liver function abnormalities may occasionally occur. Furthermore, when undergoing tests involving iodinated contrast agents, this medication should be stopped before and after the tests, and resumed only after confirming normal kidney function. Alcohol intake should be avoided while taking this medication as it may increase the risk of lactic acidosis. Patients should ensure adequate fluid intake while taking this medication and report any unusual symptoms to medical personnel immediately.

Serious side effects

• Hives
• severe swelling (angioedema)
• chest tightness
• difficulty breathing
• cold sweat
• paleness
• severe rash with fever
• blisters
• skin peeling
• pain in oral/ocular mucosa

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is best to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. This will help keep the medication effective for a longer period.

Appearance

A pinkish-white, biconvex, oval film-coated tablet

Package unit

60 tablets/bottle, 60 tablets/box [10 tablets/PTP x 6]