Empagmet Extended-Release Tablets 10/1000 mg (Empagliflozin, Metformin Hydrochloride)

Adult dose

The dosage for this medication is determined by considering each patient's current treatment, efficacy, and tolerance within the maximum daily limits of 25 mg of empagliflozin and 2000 mg of extended-release metformin hydrochloride. This medication is taken once daily at dinner time along with food. The dose of metformin hydrochloride should be increased gradually, and the tablets should be swallowed whole without splitting, crushing, or chewing. Initial recommended doses

This medication is used to control blood sugar, and should not be taken by patients with impaired kidney function or severe renal disease. This medication should also not be used in the presence of acute conditions such as severe infections, dehydration, decreased cardiac function, or acute myocardial infarction. Women who are pregnant or may become pregnant should not take this medication, and discontinuation during breastfeeding is also advisable. This medication may rarely cause a serious side effect called lactic acidosis; therefore, if symptoms such as difficulty breathing, muscle pain, abdominal pain, or weakness occur, medical consultation should be sought immediately. Additionally, if this medication is taken with insulin or sulfonylureas, there is a risk of hypoglycemia, so careful monitoring of blood sugar changes is necessary. Urinary or genital infections may occur, so prompt treatment should be sought if infection symptoms appear. When undergoing surgery or tests using iodine-based contrast agents, the use of this medication should be temporarily halted, and it should be resumed only after confirming normal kidney function. Elderly patients or those at risk of fluid loss should be cautious about dehydration and decreased blood pressure, and regular monitoring of kidney function is recommended. This medication should be swallowed whole and not crushed or chewed, and it is normal for the tablet coating to be expelled in the stool. It is advisable to avoid alcohol consumption during treatment, and since vitamin B12 deficiency may occur, blood tests should be performed if necessary. Regular consultation with medical professionals regarding blood sugar control and adverse reactions is essential while on this medication, and any abnormal symptoms should be reported immediately.

Serious side effects

Urticaria, angioedema, necrosis of the perineum, ketoacidosis, lactic acidosis, urosepsis, pyelonephritis, abnormal liver function tests, hepatitis, cerebral infarction, myocardial infarction, fever, chest pain, chest discomfort, vascular stent thrombosis, acute kidney injury, acute cholecystitis, autoimmune hepatitis, cholelithiasis, shock, cardiopulmonary disease, sepsis, pneumonia, acute congestive heart failure, acute myocardial infarction, hypoglycemia (including severe and significant hypoglycemia), difficulty breathing

Mild side effects

• Hypoglycemia
• urinary infections
• genital infections
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained between 1 to 30 degrees Celsius room temperature, which helps preserve the efficacy of the medication for a longer time.

Appearance

Dark orange oval extended-release film-coated tablets

Package unit

30 tablets/bottle