Medication info
Caraduo Tablet 20/600 mg (Rabeprazole Sodium, Precipitated Calcium Carbonate)

Caraduo Tablet 20/600 mg (Rabeprazole Sodium, Precipitated Calcium Carbonate)

Prescription medicationTablet경구
Ingredient · strength
Rabeprazole Sodium›20mg / 1 tabletPrecipitated Calcium Carbonate›490mg / 1 tablet
Manufacturer / importer
일성아이에스(주)
Appearance
Pale yellow round film-coated tablet
Packaging
28 tablets per bottle
Approval status
Active

MFDS item code 202401495 · Approved 2024.06.20 · Insurance code 655404750

Summary

Main use
Treatment of gastric ulcers and gastroesophageal reflux disease (erosive, ulcerative)
Who takes it
Adults · Children
Adult dose
1. Adults 1) Gastric ulcers, duodenal ulcers: 20/600 mg can be orally administered once daily according to symptoms. Generally, it is administered for up to 8 weeks for gastric ulcers and 6 weeks for duodenal ulcers. 2) Erosive or ulcerative gastroesophageal reflux disease: 20/600 mg is administered orally once daily for 4 to 8 weeks. If symptoms do not improve after 8 weeks of proton pump inhibitor (PPI) therapy, an additional 20/600 mg can be administered orally for 8 weeks.
Child dose
The safety of this medication has not been established in pediatric patients.

Ingredients

Manufacturer
일성아이에스(주)

Efficacy & effects

Treatment of gastric ulcers and gastroesophageal reflux disease (erosive, ulcerative)

  • Gastric ulcer
  • duodenal ulcer
  • erosive gastroesophageal reflux disease
  • ulcerative gastroesophageal reflux disease
  • gastroesophageal reflux disease
View approved original text

This medication is used to treat gastrointestinal ulcers such as gastric ulcers and duodenal ulcers. It also helps relieve erosive or ulcerative gastroesophageal reflux disease. It is effective for long-term maintenance therapy of gastroesophageal reflux disease. Therefore, it is used for the treatment of ulcers in the stomach and esophagus as well as reflux diseases.

How to take

Adult dose

1. Adults 1) Gastric ulcers, duodenal ulcers: 20/600 mg can be orally administered once daily according to symptoms. Generally, it is administered for up to 8 weeks for gastric ulcers and 6 weeks for duodenal ulcers. 2) Erosive or ulcerative gastroesophageal reflux disease: 20/600 mg is administered orally once daily for 4 to 8 weeks. If symptoms do not improve after 8 weeks of proton pump inhibitor (PPI) therapy, an additional 20/600 mg can be administered orally for 8 weeks.

Child dose

The safety of this medication has not been established in pediatric patients.

Precautions

This medication should not be used in patients with allergies or hypersensitivity to certain components. Additionally, it is contraindicated for patients taking certain antiviral medications or for women who are pregnant or breastfeeding. Caution is required for patients with severely impaired kidney function or certain metabolic disorders such as hypercalcemia. It should be used with extra caution in patients with weak liver function, the elderly, or those with a history of drug allergies. This medication may cause hypersensitivity reactions such as skin rashes, itching, or hives; if these symptoms occur, the medication should be discontinued immediately. Regular blood tests are recommended as blood cell counts may change, and liver function tests should also be conducted. Various side effects including cardiac or vascular symptoms, gastrointestinal symptoms, and neurological abnormalities have been reported; any unusual symptoms should be discussed with a healthcare professional immediately. Long-term use of this medication may increase the risk of bone fractures; hence, regular check-ups are recommended for patients on long-term therapy. Additionally, there may be a risk of hypomagnesemia with prolonged use, so magnesium levels should be checked periodically. This medication may suppress gastric acid secretion, which could increase the risk of gastrointestinal infections; thus, if diarrhea persists, healthcare professionals should be informed. Caution should be exercised when driving or operating machinery as drowsiness may occur. There may be interactions with other medications; patients should inform healthcare professionals of any other medications they are taking. Women who are pregnant or breastfeeding should not take this medication, and special caution is needed for the elderly and children. In case of overdose, there are no specific antidotes; therefore, symptomatic treatment should be administered and healthcare professionals should be followed. This medication should be swallowed whole and not chewed or crushed.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, liver abnormalities (jaundice), severe skin reactions (severe rash, blisters, skin peeling, pain in oral/ocular mucosa), serious neurological symptoms (severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis), respiratory issues (shortness of breath or difficulty breathing, asthma attacks, abnormal breathing accompanied by cough and fever), severe swelling or urinary abnormalities (urine output quantity

Mild side effects

  • Rash
  • itching
  • decreased red blood cells
  • decreased white blood cells
  • increased white blood cells
  • increased eosinophils
  • increased neutrophils
  • decreased lymphocytes
  • anemia
  • petechial hemorrhage
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  • lymphadenopathy
  • hypochromic anemia
  • pancytopenia
  • agranulocytosis
  • thrombocytopenia
  • hemolytic anemia
  • elevated ALT
  • elevated AST
  • elevated ALP
  • elevated γ-GTP
  • elevated LDH
  • elevated total bilirubin
  • hypertension
  • myocardial infarction
  • ECG abnormalities
  • migraine
  • syncope
  • angina
  • blocked conduction
  • palpitations

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is safe to store it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication.

Appearance and packaging

Appearance

Pale yellow round film-coated tablet

Package unit

28 tablets per bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.