Direx Tablets

Adult dose

For individuals aged 15 years and older, take 2 tablets at a time, three times a day, avoiding on an empty stomach. The interval between doses should be at least 4 hours.

This medicine can cause gastrointestinal bleeding in people who consume more than three alcoholic beverages daily, so consultation with a doctor or pharmacist is essential. Do not take if there is a history of allergic reactions to this medicine or any of its ingredients. Persons who have previously experienced asthma when taking this medicine or similar antipyretic analgesics or cold medications should also refrain from use. Infants under 3 months should not take this medicine. During the use of this medicine, do not take other antipyretic analgesics, cold medications, or sedatives concurrently. Infants with chickenpox or suspected influenza and children under 15 years of age should always consult a doctor before use. Those with allergic predispositions or who have experienced allergic symptoms due to medications previously should consult a doctor or pharmacist. Patients with liver, kidney, heart, thyroid disease, diabetes, hypertension, or edema, or who are frail or have a high fever should consult a professional before use. Elderly individuals, pregnant women or those who may become pregnant, and nursing mothers should also consult a professional before use. Inform the doctor or pharmacist if taking other medications, especially diabetic drugs, gout medications, arthritis medications, anticoagulants, or steroids. Those with persistent or recurrent gastrointestinal issues such as heartburn or stomach pain, or who have ulcer or bleeding problems should exercise caution. Patients experiencing dehydration due to vomiting and diarrhea, or taking diuretics should consult prior to use. If symptoms such as rash, itching, nausea, vomiting, loss of appetite, stomach pain, dizziness, or swelling occur during use, immediately stop taking the medicine and consult a professional. In case of severe allergic reactions or severe symptoms such as blisters on the skin or mucous membranes, discontinue use immediately and seek emergency care. If symptoms do not improve after 5 to 6 doses, discontinue use and consult a doctor. This medicine should not be given to children under 2 years of age unless necessary, in which case medical expertise should be sought. Strict adherence to the prescribed dosage and duration is essential, and prolonged use should be avoided. During treatment, avoid alcohol consumption, and be cautious of adverse effects when taken with certain diuretics or medications containing licorice extract. Rare but serious skin adverse reactions have been reported, so if a rash or other abnormal symptoms occur within the first month, stop taking the medicine immediately. This medicine may occasionally cause cardiovascular effects; thus, individuals with heart conditions should be particularly vigilant. Store out of reach of children, avoiding direct sunlight and keeping in a cool, dry place in a well-sealed container. To maintain quality, it is advisable not to transfer to another container.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor → severe allergic reaction
• High fever accompanied by severe rash, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes → severe skin abnormal reaction
• Asthma
• Decreased urination, swelling of the face and extremities, elevated blood pressure → severe edema or urinary abnormalities
• Severe headache, paralysis → serious neurological symptoms
• Conus syndrome (coronary artery contraction, causing myocardial infarction)

Mild side effects

• Rash
• redness (flushing)
• itching
• nausea
• vomiting
• loss of appetite
• constipation
• stomach ache
• gastrointestinal bleeding
• discomfort in the upper abdomen

Drug interactions

Do not take with other antipyretic analgesics, cold medications, or sedatives. Consult a doctor or pharmacist if taking diabetic medications, gout medications, arthritis medications, anticoagulants, steroids, diuretics, potassium-containing agents, licorice-containing agents, glycyrrhizin or its salt-containing agents, loop diuretics (furosemide, ethacrynic acid), or thiazide diuretics.

Food interactions

Do not consume alcohol while taking this medication.

This medicine should be stored in a tightly sealed container to prevent air entry, ideally at room temperature between 1°C and 30°C. Proper storage will help maintain the effectiveness of the medication.

Appearance

Blue rectangular film-coated tablets

Package unit

10 tablets (10 tablets/PTP × 1), 20 tablets (10 tablets/PTP × 2), 30 tablets (10 tablets/PTP × 3), 30 tablets/bottle, 60 tablets/bottle