Linadip Duo Extended-Release Tablet 2.5/1000 mg (Linagliptin, Metformin)

Adult dose

This medication should be taken once daily with meals, preferably with dinner. To maintain extended-release properties, do not break, crush, or chew the tablet; swallow whole. For the 5/1000 mg extended-release tablet, take 1 tablet daily. For the 2.5/1000 mg extended-release tablet, take 2 tablets daily. The initial dose is 5 mg of Linagliptin and 1000 mg of Metformin Hydrochloride.

This medication is a drug that helps control blood sugar levels. While rare, a serious condition called lactic acidosis can occur during treatment, so caution is needed. Especially, patients with allergies to any of the components included in this medication, those with type 1 diabetes, severe renal impairment, liver dysfunction, acute infections, or dehydration should not take this medication. Additionally, patients with cardiac-related diseases such as acute myocardial infarction or severe heart failure or those who are pregnant should not use this medication. Risk of hypoglycemia exists, so when used with other anti-diabetic agents or insulin, blood sugar levels should be monitored frequently, and doses may need to be adjusted as necessary. For elderly patients with renal function decline or those taking medications that may affect the kidneys, kidney function should be regularly checked. This medication should be swallowed whole and not chewed or crushed; the tablet shell may be excreted in the stool, which is normal. If symptoms such as abdominal pain, muscle weakness, breathing difficulties, severe skin rashes, or blistering skin conditions occur during treatment, consult a doctor immediately. It is recommended not to use this medication during pregnancy and lactation, and patients planning to conceive or who are pregnant should consult with their doctor. Also, this medication may interact with other drugs, so it is imperative to inform healthcare professionals before starting any new medication. Regular blood tests and physical examinations to check for adverse reactions while taking this medication are important. If an overdose occurs, seek medical attention immediately for appropriate treatment, and urgent care is needed, especially if symptoms of lactic acidosis arise. Finally, this medication should be kept out of the reach of children and stored away from moisture.

Serious side effects

Urticaria, angioedema, lactic acidosis, pancreatitis, pseudo-allergic dermatitis, angioedema, severe edema accompanied by increased blood pressure, angina, acute myocardial infarction, unstable angina, cardiac arrest, acute kidney injury, end-stage renal disease, abnormal liver function (liver function abnormalities, hepatitis, acute cholangitis, acute cholecystitis, cholangitis, cholelithiasis), acute leukemia, acute pyelonephritis, asthma, difficulty breathing, pneumonia, severe allergic reactions (urticaria, angioedema), severe and long-term

Mild side effects

Hypoglycemia, taste disorder, cough, decreased appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, oral ulcers, abnormal liver function tests, hepatitis, itching, erythema, rash, severe joint pain with disabilities, increased lipase, increased amylase, nasopharyngitis, hypersensitivity, angioedema, increased vitamin B12 absorption test results, increased serum triglycerides, increased serum creatinine, increased serum potassium, increased ALT, dizziness, drowsiness, fatigue,

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. Ideally, maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Yellow, oval-shaped, bilayered extended-release film-coated tablet

Package unit

30 tablets/bottle