Kratin Tablet 2.5 mg (Rosuvastatin Calcium (Unrefined))

Adult dosage

This medication can be administered at any time of the day regardless of meals. The initial dose is 2.5 or 5 mg once daily, and for patients needing more LDL cholesterol reduction, the dose can be adjusted to a maintenance dose. The maintenance dose is 10 mg once daily for most patients, at this dosage control is achieved. The maintenance dose should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more.

This medication should not be used in patients who are allergic to certain components. Patients with severely impaired liver function or unexplained elevation of liver enzyme levels should also avoid administration. It is safer not to use it in patients with muscle diseases or abnormalities in muscle. Caution is needed as the risk of muscle problems may increase when taken with certain medications. Patients with severely impaired kidney function and women who are pregnant or breastfeeding should not take this medication. Women with a possibility of pregnancy should take this medication only if the chance of becoming pregnant is very low and must use appropriate contraceptive measures. High-dose administration is prohibited for patients at high risk of myopathy or rhabdomyolysis. This medication contains lactose, so patients with lactose intolerance or related genetic disorders should not take it. Patients with a history of alcohol consumption or liver disease should undergo regular liver function tests, and if they have hypothyroidism or nephrotic syndrome, these conditions should be treated first. If symptoms such as muscle pain, weakness, or cramps appear, they must inform their doctor immediately and may need to check for muscle damage through blood tests. If severe muscle abnormality symptoms appear, discontinue the medication and follow the doctor's instructions. This medication may temporarily elevate liver enzyme levels in some patients, so liver function tests may be necessary. When taking this medication with certain drugs, caution is advised as the drug concentration may increase, raising the risk of side effects. It should not be used during pregnancy or breastfeeding, and women planning to become pregnant must consult a doctor before taking it. There is no specific antidote for overdose, so treatment according to symptoms and monitoring of liver and muscle enzyme levels are necessary. This medication can cause dizziness; hence caution is warranted when driving or operating machinery.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough + fever, jaundice (yellowing of skin or eyes), extreme weakness throughout the body, sudden and very severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination.

Mild side effects

• Dyspepsia
• itching
• headache
• dizziness
• constipation
• nausea
• abdominal pain
• diabetes
• rash
• muscle pain

This medication may be sensitive to air and moisture; therefore, it must be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. This way, the medication's efficacy can be preserved for a longer duration.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle