Jadion Duo Tablet 12.5/500 mg

Adult dose

The recommended dose of this medication is 1 tablet, taken twice daily. The dosage should be determined considering each patient’s treatment regimen, efficacy, and tolerability, without exceeding 25 mg of empagliflozin and 2000 mg of metformin. For patients who do not achieve sufficient blood sugar control with metformin alone or in combination with other medications, treatment can begin with 5 mg of empagliflozin taken twice daily (total daily dose of 10 mg) along with their existing metformin dosage.

This medicine can cause a rare complication known as severe lactic acidosis; thus, patients should consult a doctor immediately if symptoms appear. Caution is also necessary when used with other diabetes medications as this may result in hypoglycemia. It should not be used in patients with moderate to severe renal impairment. It should also be avoided in cases of acute renal issues, severe infections, or heart problems. Pregnant or breastfeeding women should not take this medicine. Kidney function tests should be performed before starting this medication, and renal function should be regularly monitored during treatment. Use of this drug may be temporarily halted in situations posing a risk of fluid loss such as dehydration, vomiting, or diarrhea. It may increase the risk of urinary tract infections and genital infections, so any signs of infection should be reported immediately. Patients with impaired liver function must also use this medicine with caution. Patients scheduled for surgery should stop this medication 48 hours prior to surgery and can resume after renal function has returned to normal post-operation. Avoiding alcohol consumption during the period of taking this medication is recommended. Elderly patients or those with impaired renal function should take this medication with particular caution and may require dosage adjustments. Symptoms of hypoglycemia may appear while taking this medication, and immediate action should be taken if symptoms occur. Regular blood tests are recommended as blood levels of vitamin B12 may decrease. Regular testing should be conducted to check for adverse reactions, and if any abnormal symptoms occur, a doctor should be consulted immediately.

Serious side effects

• Hives
• severe swelling (angioedema)
• ketoacidosis
• lactic acidosis
• necrosis of the perineum
• severe allergic reactions
• severe skin reactions
• difficulty breathing
• asthma attacks
• breathlessness

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medicine should be stored in a tightly closed container away from air and moisture, and it is best kept at room temperature between 1 and 30 degrees Celsius. This storage condition helps maintain the effectiveness of the drug and prevents degradation.

Appearance

Biconvex, oval film-coated tablet with a light brownish-purple color

Package unit

60 tablets/bottle, 30 tablets/bottle, 60 tablets/box [(10 tablets/PTP x 6)], 10 tablets/box [(10 tablets/PTP x 1)]