Aria DS Tablets

Adult dose

Adults: Take 1 tablet twice daily. This medicine may be taken with or without food. Take this medicine whole; do not crush or split it. ○ Patients with hepatic impairment This medicine is not recommended for initial treatment in patients with hepatic impairment who require a dose reduction (see Precautions for Use, 5. General Precautions)

This medication should be discussed with a doctor or pharmacist before use by individuals who regularly consume more than three drinks per day, as there is an increased risk of gastrointestinal bleeding when taken by heavy drinkers. This medication may increase the risk of serious cardiovascular diseases such as thrombotic events, myocardial infarction, and stroke. This risk may increase depending on the dose and duration of treatment, so it should be taken at the minimum effective dose for the shortest duration. Additionally, this medication can cause gastrointestinal adverse reactions such as gastrointestinal perforation, ulcers, and bleeding. Special caution is required for the elderly or patients with a history of gastrointestinal diseases, and if symptoms of gastrointestinal bleeding or ulcers occur, medical attention should be sought immediately. This medication is contraindicated for patients with specific allergic reactions, severe cardiovascular, liver, or kidney diseases, active gastrointestinal bleeding, inflammatory bowel disease, as well as pregnant and breastfeeding women. Patients with impaired liver or kidney function, asthma, heart failure, hypertension, fluid retention, and the elderly should be monitored more closely while taking this medication. While taking this medication, adverse reactions such as headache, dyspepsia, edema, rash, and elevated blood pressure may occur, and if any abnormal symptoms persist or worsen, medical advice should be sought immediately. This medication may interact with other medications, so it is important to inform the doctor, especially if taking medications metabolized by the liver, antihypertensive medications, anticoagulants, or diuretics. Women who are pregnant or may become pregnant should not take this medication, and breastfeeding mothers are also advised to avoid it. Safety and efficacy have not been established for children and adolescents under 18 years of age, so it should not be used in this population. Elderly patients are at higher risk for decreased kidney, liver, and heart function, and caution is needed when taking this medication, including possible dose adjustments. Regular blood tests and liver and kidney function tests should be conducted during treatment to monitor for abnormalities, and if any abnormal findings are noted, the medication should be stopped immediately. If symptoms such as dizziness or drowsiness occur after taking this medication, driving or operating machinery should be avoided. In cases of overdose, symptoms such as nausea, vomiting, drowsiness, and gastrointestinal bleeding may occur, requiring immediate emergency treatment. This medication should be stored out of reach of children and should not be transferred to other containers.

Gastrointestinal bleeding, cardiovascular thromboembolic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, dyspepsia, nausea, epigastric pain, constipation, diarrhea, dry mouth, esophageal pain, stomatitis, COVID-19, acute pyelonephritis, facial swelling, pain at the site of insertion, peripheral edema, fever, pruritus, psoriasis, rash, dermal swelling, alanine aminotransferase elevation, aspartate aminotransferase elevation, increased blood pressure, increased blood uric acid, gamma-glutamyltransferase elevation, arthralgia, back pain, coccydynia, flank pain, headache, carpal tunnel syndrome, lymphadenopathy, cholelithiasis, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, distension, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, liver enzyme elevation, itching, urticaria, angioedema, alopecia, vesicular dermatitis, peripheral edema, influenza-like illness, injury, decreased hematocrit, increased hemoglobin, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, skin nodules, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, clouded vision, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine occult blood, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, headache, dizziness, drowsiness, heartburn, dry mouth, nausea, diarrhea, weakness, hypertriglyceridemia, hypercholesterolemia, transaminitis, elevated ALT, elevated AST, itching, leukopenia, neutropenia, chest discomfort, upper respiratory tract infection, blurred vision, gastritis, gastroesophageal reflux, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, female infertility, chest pain, vasculitis, angioedema, anaphylactic-like reaction, skin rash, mucosal lesions, vesicles, fever, itching, bronchospasm, asthma exacerbation, lethargy, drowsiness, nausea, vomiting, epigastric pain, worsening hypertension, respiratory depression, coma

This medication is sensitive to air and moisture; therefore, it should be stored in a tightly closed container. It is recommended to store it at room temperature between 1 to 30 degrees Celsius. Avoid locations that are too hot or too cold, and keep it in a cool place out of direct sunlight.

Appearance

Yellow rectangular film-coated tablet consisting of two layers

Package unit

30 tablets/bottle, 300 tablets/bottle