Janugriptin Duo XR Controlled Release Tablet 100/1000 mg

Adult dose

The 100/1000 mg controlled-release tablet should be taken once daily, one tablet at a time. Patients taking the 50/500 mg controlled-release tablet or the 50/1000 mg controlled-release tablet should take it once daily, two tablets at a time. 1. Patients not currently treated with metformin: The initial dose is a total daily dose of 100 mg of sitagliptin and 1000 mg of metformin. 2. Patients on metformin...

This medication is used for the treatment of diabetes, and caution should be exercised as some patients may experience serious allergic reactions. Symptoms of acute pancreatitis may occur while taking this medication, so it is important to closely monitor for symptoms such as abdominal pain or vomiting. This medication should not be used in patients with severely impaired renal function or specific diseases such as acute heart failure or myocardial infarction. Moreover, the use of this medication should be temporarily discontinued before and after tests involving radiopaque agents, and it should only be restarted after confirming normal kidney function. It is advisable not to use this medication during pregnancy or breastfeeding, as its safety has not been established in these populations. This medication can cause hypoglycemia, so regular meals and adjustment of exercise and medication intake are necessary, and immediate action should be taken if symptoms of hypoglycemia occur. In patients with reduced liver or kidney function, there is a risk of a serious side effect known as lactic acidosis, and regular blood tests and kidney function tests are needed. Excessive alcohol consumption may increase the risk of side effects from this medication, so it is best to avoid it. If surgery is to be performed, this medication should be discontinued 48 hours before the procedure, and it should be restarted only after normal oral intake has recovered. During the course of treatment, blood sugar, kidney function, and hematological values should be regularly monitored, and if any unusual symptoms arise, immediate consultation with healthcare personnel is required. Additionally, there may be interactions with specific medications, so all medications being taken should be communicated to healthcare personnel. Some patients may experience severe arthralgia or skin disorders, so if symptoms occur, they should inform their physician immediately. In case of overdose, seek medical attention promptly for appropriate treatment, and blood dialysis may be necessary.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, rash, exfoliative skin disorders, Stevens-Johnson syndrome, life-threatening hemorrhagic or necrotizing pancreatitis, acute pancreatitis, acute renal failure, severe hypoglycemia, elevated liver enzymes, liver abnormalities (jaundice), severe arthralgia accompanied by disability, bullous pemphigoid, angioedema, severe allergic reactions, severe skin adverse reactions, liver abnormalities (jaundice), severe edema or urination issues

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• upper respiratory tract infection
• nasopharyngitis
• headache
• hypoglycemia
• arthralgia
• myalgia

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius to preserve the efficacy of the medication for a longer period.

Appearance

Bright blue, double-convex, oval-shaped controlled-release film-coated tablet

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle