Janusit Met XR Controlled-release Tablet 100/1000 mg

Adult dose

This medication in a 100/1000 mg controlled-release form is taken once daily, with one tablet per dose. Patients taking the 50/500 mg controlled-release form or the 50/1000 mg controlled-release form should take two tablets simultaneously once daily. 1. Patients not currently treated with metformin: The initial dosage is a total daily amount of 100 mg of sitagliptin and 1000 mg of metformin. If the dosage is insufficient,

This medication is used for the treatment of diabetes, and allergic reactions may occur during use. If symptoms such as skin rash, hives, or difficulty breathing appear, you should stop taking the medication immediately and consult a doctor. This medication can cause serious inflammation of the pancreas called pancreatitis, so if symptoms like abdominal pain, nausea, or vomiting occur, you should inform medical personnel immediately. Patients with severe renal impairment, dehydration, severe infections, or heart disease should not take this medication. Especially before and after tests using radiographic iodinated contrast agents, the intake of this medication should be temporarily discontinued, and it should be resumed only after confirming normal kidney function. Women who are pregnant, possibly pregnant, or breastfeeding should not take this medication. Care should be taken during irregular meals, nutritional deficiencies, or intense exercise. Patients allergic to certain dyes should use this medication with caution. During use, be careful of hypoglycemic symptoms, and if taken with other hypoglycemic agents, the risk of hypoglycemia may increase, so blood sugar should be monitored frequently. This medication can affect liver and kidney function, so regular blood tests and kidney function tests should be performed, and any abnormal signs should be reported to a doctor immediately. Alcohol consumption may increase the risk of side effects, so it is advisable to avoid drinking while taking this medication. If surgery is planned or has recently occurred, this medication should be discontinued for a certain period, and resumed only after the patient’s condition stabilizes. Elderly patients should monitor their kidney function and adjust dosage, as renal function may decline.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, rash, cutaneous vasculitis, desquamating skin diseases such as Stevens-Johnson syndrome, fatal/non-fatal hemorrhagic or necrotizing pancreatitis, acute pancreatitis, acute renal failure, elevated liver enzymes, bullous pemphigoid, severe hypoglycemia, lactic acidosis, acute renal function deterioration, liver abnormalities (suspected jaundice), serious neurological symptoms (severe headache, confusion, seizures, etc.)

Mild side effects

Diarrhea, upper respiratory infection, headache, nausea, vomiting, abdominal pain, constipation, nasopharyngitis, muscle pain, limb pain, back pain, interstitial lung disease, itching, thrombocytopenia, rhabdomyolysis, hypoglycemia, reduction in vitamin B12, severe arthralgia accompanied by disability

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. It is important to maintain the storage temperature between 1 to 30 degrees Celsius at room temperature.

Appearance

Light blue, double convex, oval-shaped controlled-release film-coated tablet

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle