Dapduo Sustained Release Tablet 10/1000 mg

Adult dose

This medication is generally administered once daily with the evening meal. The maximum dosage is 10 mg of dapagliflozin and 2000 mg of sustained-release metformin once daily, which can be taken as two tablets of 5 mg/1000 mg. For patients without prior experience with diabetes medication treatment and having difficulty with blood glucose control alone, the initial dosage for therapy is one tablet of 5 mg/500 mg or 10 mg/500 mg taken once daily.

This medication is used for diabetes treatment and helps manage blood sugar levels. When taking this medicine, one should be cautious of rare side effects such as severe lactic acidosis. Lactic acidosis is a potentially dangerous condition where lactic acid accumulates excessively in the body. Additionally, careful monitoring is required when used in conjunction with insulin or sulfonylurea medications, as it may cause severe hypoglycemia. Patients with poor kidney function, dehydration, severe infections, or heart issues should not take this medication. Before and after surgeries or tests using radioactive iodine contrast agents, the use of this medication should be temporarily discontinued, and it should only be resumed after confirming normal renal function. Pregnant or breastfeeding women should not use this medication, and patients with specific genetic disorders such as lactose intolerance should also avoid it. Elderly patients or those with diminished kidney function should undergo kidney function tests before taking this medication, and regular monitoring of kidney function should continue during treatment. This medication can cause a decrease in fluid volume or low blood pressure, so patients with low blood pressure or those taking diuretics should be especially cautious. Genital infections and urinary tract infections may occur frequently, so patients should consult a healthcare professional immediately if infection symptoms appear. Vitamin B12 levels may decrease, so it's advisable to check vitamin B12 levels during long-term use. Excessive alcohol consumption can increase the risk of side effects associated with this medication, so it should be avoided. This medication may cause hypoglycemia, and dosage adjustments may be necessary when taken with insulin or other hypoglycemic agents. In case of overdose, seek immediate medical attention for appropriate treatment. During treatment, dizziness may occur while driving or operating machinery, so caution is advised. Lastly, this medication should be stored out of reach of children and kept in its original container to maintain quality.

Serious side effects

• Severe lactic acidosis
• severe hypoglycemia
• Guillain-Barré syndrome
• bacterial pneumonia
• sialadenitis
• chest pain
• heat burns
• wrist fractures
• gastrointestinal stromal tumors
• malignant lung neoplasms

Mild side effects

Hypoglycemia, dry mouth, constipation, low back pain, dysuria, polyuria, nocturia, pruritus of the external genitalia, genital itching, increased hematocrit, early treatment renal creatinine clearance decline, dyslipidemia, early treatment blood creatinine increase, blood urea increase, weight loss, dizziness, fungal infections, urinary tract infections, pruritus, headache, paresthesia, tremors, weakness, fatigue, edema, hyperglycemia, benign prostatic hyperplasia,

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. Moreover, it is best stored at room temperature, which is neither too hot nor too cold, between 1 to 30 degrees Celsius.

Appearance

Yellow, biconvex, oval-shaped sustained-release film-coated tablet

Package unit

30 tablets/box [(6 tablets/PTP*5)], 200 tablets/bottle, 30 tablets/bottle