Ibukay Injection (Ibuprofen)

Adult dosage

For adjunct therapy in the management of moderate to severe pain, administer intravenously 400 mg to 800 mg every 6 hours as needed. The maximum daily dose can be up to 3200 mg, with an administration time of more than 30 minutes. For antipyretic purposes, administer intravenously 400 mg every 4 to 6 hours as needed. Based on the patient's condition, after the initial dose of 400 mg, an additional dose every 4 hours may be 100-200 mg.

Children's dosage

For children aged 6 months to under 12 years, administer intravenously starting at 10 mg/kg (maximum 400 mg) every 4 to 6 hours as needed, ensuring administration time is more than 10 minutes. Maximum daily dose is 40 mg/kg.

This drug may increase the risk of serious cardiovascular problems such as myocardial infarction and stroke in patients with cardiovascular disease or risk factors. The risk increases, especially with long-term use at high doses. This medication can cause serious gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, and perforation, particularly in the elderly or long-term users. Therefore, gastrointestinal symptoms should be closely monitored during treatment. Patients with a history of gastrointestinal ulcers or bleeding, severe blood, liver, kidney, or heart diseases, and those allergic to any components of this drug should not use it. Additionally, patients who have experienced hypersensitivity reactions to aspirin or have asthma should avoid this medication. Those with blood abnormalities, liver or kidney impairment, heart failure, hypertension, autoimmune diseases, ulcerative colitis, Crohn's disease, the elderly, pregnant women, and breastfeeding mothers require careful observation and dosage adjustments when using this drug. In particular, late-stage pregnancy should be avoided due to potential risks to the fetus. This medication can cause various severe adverse reactions, such as allergic reactions, blood abnormalities, gastrointestinal bleeding, skin rashes, liver function impairment, kidney issues, and neuropsychiatric symptoms. It's important not to exceed the recommended dosage and not to use it in combination with other non-steroidal anti-inflammatory drugs. Before use, careful consideration of the risks and benefits should be made, aiming for the minimum effective dose for the shortest duration. Patients with hypertension should frequently monitor their blood pressure, as this medication may worsen the condition. Caution is also required in patients with heart failure or edema. Patients with compromised kidney function or those in a dehydrated state should be particularly cautious when taking this drug, and those with liver function impairment should undergo regular monitoring of liver function. Drug interactions may occur when taking this medication with aspirin or anticoagulants, diuretics, lithium, methotrexate, etc., so consultation with healthcare professionals is essential. Pregnant women, especially in the late stages of pregnancy, should avoid this medication due to its potential severe effects on the fetus, and breastfeeding mothers should consider discontinuing breastfeeding while taking this medication. Safety and efficacy have not been established in children under 6 months of age, thus it is advisable not to use it in this population. Elderly patients have decreased physical function and require dosage adjustments and close monitoring. In cases of overdose, serious symptoms such as dizziness, nausea, vomiting, liver dysfunction, kidney failure, respiratory distress, and hypotension may occur; immediate discontinuation and medical treatment are necessary.

Serious side effects

Urticaria, hypotension, hypertension, palpitations, heart failure, myocardial infarction, angina, asthma, bronchoconstriction, respiratory distress, wheezing, shock, anaphylactic reactions, blood abnormalities (agranulocytosis, granulocytopenia, leukopenia, thrombocytopenia, aplastic anemia, hemolytic anemia), peptic ulcer, gastrointestinal ulcer, gastrointestinal bleeding, perforation, ulcerative colitis, hematochezia, pancreatitis, hematemesis, Crohn's disease, Stevens-Johnson syndrome

Mild side effects

• Nausea
• vomiting
• bloating
• headache
• hemolysis
• drowsiness
• dyspepsia
• diarrhea
• anemia
• increased hematuria

This medication should be stored in a sealed container to prevent air exposure and kept at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the drug's efficacy and prevents degradation.

Appearance

A clear or pale yellow liquid filled in a colorless, transparent plastic container.

Package unit

100 milliliters/vial, 200 milliliters/vial