Empagliflozin/Metformin Duo Tablets 5/850 mg

Adult dose

The recommended dose of this medication is 1 tablet per dose, taken twice daily. Dosages should be determined considering each patient's current therapy, efficacy, and tolerability, without exceeding 25 mg of empagliflozin and 2000 mg of metformin. For patients who cannot achieve adequate blood glucose control with metformin alone or in combination with other medications such as insulin, the recommended dosage is 5 mg of empagliflozin twice daily (

This medication helps control blood sugar levels. It may cause a rare side effect known as lactic acidosis, which is a serious condition where lactic acid builds up excessively in the body. Lactic acidosis is severe and can sometimes be fatal, so immediate consultation with a physician is necessary if symptoms occur. Additionally, the risk of hypoglycemia may increase when this medication is taken with other diabetes medications such as insulin or sulfonylureas. Symptoms of hypoglycemia include dizziness, cold sweat, and severe fatigue. This medication should not be used in patients with significantly impaired kidney function or in acute conditions such as infections, dehydration, heart failure, or acute myocardial infarction. Women who are pregnant or may become pregnant and nursing mothers should also avoid this medication. During treatment, regular monitoring of kidney function is necessary, as treatment may be stopped if there is a decline in kidney function. When undergoing imaging tests with iodine contrast agents, this medication should be suspended for a certain period before and after the test, and it should be resumed only after confirming normal kidney function. This medication may lead to fluid loss, so patients at risk for dehydration or low blood pressure should use caution. Elderly patients or those with cardiovascular conditions should be especially careful. During treatment, urinary and genital infections may occur, and any related symptoms should be reported to a physician immediately. The metformin component may cause gastrointestinal disturbances (diarrhea, nausea, vomiting, etc.) and may lower vitamin B12 levels, so regular monitoring may be required. Alcohol use can increase the risk of lactic acidosis; therefore, it is advisable to avoid drinking alcohol while on this medication. Women who are pregnant or nursing should not take this medication, and if they are currently taking it, they should consult their doctor. This medication is not recommended for children under 18 years of age. In the case of overdose, there is a risk of lactic acidosis or hypoglycemia, and immediate medical attention is required, possibly needing treatment via hemodialysis. Patients should have their blood sugar and kidney function, as well as vitamin B12 levels, regularly monitored during treatment, and should consult their doctor immediately if any abnormal symptoms occur. Additionally, this medication may interact with other drugs, so it is essential to inform healthcare providers of other medications being taken.

Serious side effects

Hives, angioedema, perineal necrosis, ketoacidosis, lactic acidosis, urosepsis, pyelonephritis, myocardial infarction, cerebral infarction, acute kidney injury, liver abnormalities (hepatitis, autoimmune hepatitis, acute cholecystitis, cholelithiasis), sudden and severe headache, seizures, confusion, visual disturbances, paralysis, difficulty breathing, asthma attacks, severe edema, increased blood pressure, heart failure, shock, acute congestive heart failure, acute myocardial infarction, acute

Mild side effects

• Hypoglycemia
• urinary tract infections
• genital infections
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication may be sensitive to air or humidity, so it must be stored in a tightly sealed container. It is important to maintain storage temperatures between 1 to 30 degrees Celsius at room temperature to preserve the medication's effectiveness for a longer period.

Appearance

White, oval, biconvex, film-coated tablets with a yellow tint

Package unit

10 tablets/box[(10 tablets/PTP x 1)], 60 tablets/box[(10 tablets/PTP x 6)], 60 tablets/bottle