Rabecombi Tablet

Adult dose

For gastric ulcers and duodenal ulcers: Administer orally 20/800 mg once daily, depending on symptoms. Typically, treatment continues for 8 weeks for gastric ulcers and 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: Administer 20/800 mg once daily for 4 to 8 weeks. If unresolved after 8 weeks of proton pump inhibitor (PPI) therapy, an additional 20/800 mg can be administered orally twice daily for another 8 weeks, particularly for patients with confirmed severe mucosal damage. For long-term maintenance therapy of gastroesophageal reflux disease: 20/800 mg may be taken orally once a day, depending on the patient. ◯ In patients with liver dysfunction: Abnormal reactions of hepatic encephalopathy have been reported in patients with liver cirrhosis; therefore, caution should be exercised. ◯ In children: Safety for use in children has not been established. ◯ In the elderly: Care should be taken as often there is decreased liver function.

Child dose

Safety for use in children has not been established.

This medication should not be administered to patients with a known allergy to its components or to those who have experienced hypersensitivity reactions. Additionally, caution is advised when taken in combination with certain antiviral agents, as drug interactions may reduce efficacy. Pregnant or breastfeeding women should also avoid this medication. Patients with poor liver or kidney function, elderly patients, and those with heart or lung problems should use this drug more cautiously. In particular, if there is an electrolyte imbalance, caution is necessary due to the potential exacerbation of the condition from the components of this medication. If allergic symptoms such as skin rash, itching, or difficulty breathing occur during treatment, discontinue immediately and consult a physician. Regular blood tests or liver function tests are recommended, and if any abnormal signs are detected, discontinue the medication and seek appropriate treatment. Gastrointestinal symptoms may include abdominal pain, diarrhea, nausea, vomiting, etc., and in rare cases, serious hepatitis or pancreatitis may occur. Neurological symptoms may include headaches, dizziness, insomnia, and depression, with rare occurrence of seizures or confusion. Respiratory issues may arise, so caution is needed if there are cough or breathing difficulties. Muscle pain, joint pain, skin rashes, and hair loss have also been reported; if symptoms persist, it is advisable to inform a doctor. Long-term use of this medication may increase the risk of bone fractures, so regular check-ups are necessary for prolonged treatment. Additionally, long-term use may cause hypomagnesemia, necessitating monitoring magnesium levels and supplementation if necessary. This medication may increase the risk of bacterial infections in the stomach by suppressing gastric acid secretion, so if diarrhea persists, consult healthcare professionals. Caution is needed when driving or operating machinery as drowsiness may occur. This medication can interact with other drugs, so inform your healthcare provider of any other medications being taken, especially when combined with anticoagulants or antiviral agents. In case of overdose, no specific antidote is available, and treatment should be symptomatic under the direction of healthcare professionals. This medication should be swallowed whole without chewing or crushing, and it should be kept out of reach of children. It should not be used during pregnancy or breastfeeding, and elderly patients should be cautious due to the risk of side effects from decreased liver function. Safety for use in children has not been established, thus its use is not recommended. Prolonged use of this medication may increase the risk of polyps in the stomach, necessitating regular check-ups. Serious kidney diseases such as acute interstitial nephritis may occur, so if there are signs of impaired kidney function, consult a physician immediately.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor (severe allergic reaction), severe rash with high fever, blisters, skin peeling, painful mucosal lesions in the mouth/eyes (severe dermatological reactions), difficulty or inability to breathe, asthma attacks, respiratory issues accompanied by cough and fever (respiratory problems), yellowing of the skin or eyes (jaundice), extreme lethargy (liver abnormalities), sudden and

Mild side effects

Occasional side effects may include rash, itching, blood system abnormalities (such as decreased red blood cells and white blood cells), elevated liver enzymes, hypertension, migraine, fainting, angina, palpitations, diarrhea, constipation, abdominal pain, dyspepsia, nausea, vomiting, headaches, insomnia, anxiety, dizziness, cough, pharyngitis, muscle pain, joint pain, sweating, hair loss, cataracts, dry eyes, urinary difficulties, edema, fever, urinary tract infections, weight changes, visual disturbances, palpitations, chest tightness, facial

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container at room temperature. It is best to maintain a storage temperature between 1 degree and 30 degrees. This will help to preserve the medication’s efficacy over time.

Appearance

White oval film-coated tablet

Package unit

28 tablets/box [7 tablets/PTP x 4EA], 30 tablets/box [10 tablets/PTP x 3EA]