Dapadi Tablet 10 mg (Dapagliflozin Propanediol Monohydrate)

Adult dose

The recommended dose of this medication for monotherapy and adjunctive therapy is 10 mg once daily. For initial combination therapy, if there is no history of prior diabetes medication treatment, it can be administered in combination with metformin at 5 mg or 10 mg once daily. It may be taken orally at any time of the day, regardless of food intake, and the tablet should be swallowed whole.

Child dose

The efficacy and safety of dapagliflozin in pediatric patients under the age of 18 have not been established. There is no relevant data.

This medication should not be administered to certain patients. For example, it should not be used by individuals who are allergic to any of its components, patients with type 1 diabetes, patients with diabetic ketoacidosis, or those undergoing dialysis. Caution should be exercised when prescribing this medication to patients with reduced fluid volume or impaired kidney function. This drug can lower blood pressure or affect kidney function, so special care is needed for the elderly or patients taking diuretics. While taking this medication, symptoms of side effects such as hypoglycemia, genital infections, urinary tract infections, reduced fluid volume, and diabetic ketoacidosis should be carefully monitored. Especially, genital infections may occur more commonly in women, and those with a history of prior infections may have a higher risk of recurrence. The risk of hypoglycemia may increase when this medication is used in conjunction with drugs that can induce hypoglycemia such as insulin or sulfonylureas, and dose adjustments may be necessary. Women who are pregnant or breastfeeding should avoid using this medication, and it should be discontinued if pregnancy is confirmed. The safety and efficacy of this medication have not been established in children, so it is not used in this population. In the event of an overdose, there is no specific antidote, so appropriate treatment should be provided based on symptoms, and careful management of dehydration and hypotension symptoms is required. This medication does not have a significant impact on driving or machine operation, but caution is needed when taken with medications at risk for hypoglycemia. Finally, this medication should be stored in its original container, out of the reach of children, and it is safest not to change the container arbitrarily.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, oral/eye mucosal pain, shortness of breath or difficulty breathing, asthma attacks, respiratory issues with cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urinary abnormalities

Mild side effects

Vulvovaginitis, balanitis and related genital infections, urinary tract infections, fungal infections, hypoglycemia, thirst, dizziness, constipation, dry mouth, back pain, dysuria, polyuria, nocturia, interstitial nephritis, elevated hematocrit, increased serum creatinine, dyslipidemia, weight loss, rash, angioedema, gastrointestinal disorders (gastroesophageal reflux disease, upper abdominal pain, diverticulitis, intestinal perforation, acute pancreatitis, chronic pancreatitis, chronic gastritis, intestinal gas retention)

This medication should be stored in a tightly closed container to protect it from air and moisture, ideally at a temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the drug's effectiveness.

Appearance

Yellow, biconvex, diamond-shaped film-coated tablet

Package unit

28 tablets/PTP [7 tablets/Alu-Alu x 4], 30 tablets/bottle, 28 tablets/bottle