Dangi Jano Kombi Tablet 50/850 mg

Adult dose

This medication is generally taken twice daily with food, and the dosage is gradually increased to reduce gastrointestinal adverse effects due to metformin. 1. For patients not receiving metformin treatment, the initial dose is 50/500 mg taken twice daily, with the option to increase to 50/1000 mg. 2. For patients already receiving metformin treatment, take sitagliptin 50 mg twice daily and adjust metformin as needed.

This medication contains sitagliptin and metformin, which help control blood sugar. A rare but serious allergic reaction may occur during the use of this medication, so if symptoms such as skin rash or difficulty breathing appear, you should discontinue use immediately and consult a physician. Also, there is a risk of pancreatitis (inflammation of the pancreas) with this medication, so if sudden abdominal pain, nausea, or vomiting occurs, inform your healthcare provider immediately. Due to the metformin component, this medication should not be used in patients with poor kidney function, severe infections, or dehydration, and regular checks of kidney function should be conducted. Pregnant or breastfeeding women should not use this medication, and its safety and efficacy have not been established in children and adolescents under 18 years of age. Excessive alcohol intake should be avoided during treatment with this medication, especially in cases of reduced liver or kidney function. Hypoglycemia may occur, so caution is required if meals are skipped or vigorous exercise is noted, especially when taken in conjunction with insulin or sulfonylureas, increasing the risk of hypoglycemia. This medication should be temporarily discontinued before and after surgery or tests that use iodine contrast agents, and restarted only after recovery. Furthermore, this medication may interact with other drugs, so be sure to inform your doctor or pharmacist of any other medications you are taking. Long-term use of this medication may lower vitamin B12 levels, so regular blood tests are recommended. Finally, it is important to consult healthcare professionals immediately for any unusual symptoms or discomfort that may arise during treatment.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormality with cough and fever, breathing problems, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities.

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• headache
• upper respiratory infection
• nasopharyngitis
• constipation
• myalgia
• limb pain

Store this medication in a tightly sealed container to prevent air exposure, and keep it at room temperature between 1 degree and 30 degrees Celsius. This helps maintain the medication's efficacy.

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/box[(10 tablets/PTP x 3)]