Empagliflozin 25 mg (Empagliflozin)

Adult dose

The recommended dosage for this medication as monotherapy and in addition to other blood glucose-lowering agents, such as insulin, is 10 mg once daily. If the 10 mg dose of this medication is well tolerated and additional blood sugar control is needed, the dose may be increased to 25 mg once daily. This medication can be taken regardless of meals. The tablet should be swallowed whole. If a dose is missed, take it as soon as remembered.

This medication should not be used in certain patients, such as those allergic to its ingredients, type 1 diabetes patients, patients with severely impaired kidney function, and those with genetic issues like lactose intolerance. For patients with slightly impaired kidney function, dosage adjustment is needed, and treatment should be discontinued in cases of severe kidney impairment. Additionally, this medication is not effective in patients with end-stage kidney disease or those on dialysis. In patients with mild to moderate heart failure, it should be used cautiously, and it is not recommended for patients with severe heart failure. The risk of hypoglycemia may increase when this medication is used in conjunction with insulin or insulin-releasing agents; therefore, dosage adjustments for those medications may be necessary. During the use of this medication, side effects such as hypoglycemia, urinary infections, genital infections, increased urination, fluid loss, etc., may occur, so caution is advised. Particularly careful monitoring is needed for elderly patients or those at risk of fluid loss. Furthermore, this medication can induce serious metabolic acidosis known as ketoacidosis, so if symptoms occur, immediate consultation with healthcare professionals is necessary. Ketoacidosis can manifest as symptoms such as vomiting, abdominal pain, and difficulty breathing. It is advisable to avoid using this medication during pregnancy, and breastfeeding women are recommended to stop breastfeeding. Safety and efficacy have not been established in children and adolescents, so they should not take this medication. No specific toxicity has been reported in cases of overdose, but appropriate management may be required based on clinical condition. Consider potential drug interactions when taking this medication, especially caution is needed when used concurrently with diuretics, insulin, sulfonylureas, etc. Lastly, when storing this medication, keep it out of reach of children and do not transfer it to other containers.

Serious side effects

• Hives
• angioedema
• perineal necrosis
• ketoacidosis
• urosepsis
• pyelonephritis

Mild side effects

• Hypoglycemia
• ketoacidosis
• rash
• itching
• increased urination
• urination difficulties
• increased serum lipids
• increased serum creatinine
• decreased glomerular filtration rate
• increased hematocrit

This medication should be stored in a tightly closed container to protect it from exposure to air, and it is best to keep it at room temperature between 1 to 30 degrees Celsius. By storing it this way, you can safely maintain the efficacy of the medication.

Appearance

Light yellow oval film-coated tablet

Package unit

PTP - 30 tablets/PTP [30 tablets/PTP x 3], PTP - 10 tablets/PTP [10 tablets/PTP x 1]