Sitifor Tablet 50mg (Sitagliptin Hydrochloride Monohydrate)

Adult dosage

The usual dose is 100 mg once daily when used alone or in combination, and the maximum dose per day is 100 mg. Patients with renal impairment may need dosage adjustments based on their kidney function. For patients with moderate renal impairment (glomerular filtration rate 30-45 mL/min/1.73 m2), the dose of 50 mg once daily is recommended. For patients with severe renal impairment (glomerular filtration rate 15-30 mL/min/1.73 m2) or end-stage renal disease.

This medication can cause serious allergic reactions, so if symptoms such as skin rash or difficulty breathing occur, you should stop taking it immediately and consult a doctor. Also, severe pancreatitis, a serious inflammation of the pancreas, may occur, so if symptoms like abdominal pain, vomiting, or decreased appetite appear during treatment, you should visit a hospital immediately. Patients with type 1 diabetes or those with specific allergic reactions should not take this medication. Patients with impaired kidney function may need dosage adjustments, and it is important to have regular kidney function tests both before and during treatment. This medication can be used alone or in combination with other diabetes treatments, and when combined, there may be an increased risk of hypoglycemia, so changes in blood sugar should be carefully monitored. During treatment with this drug, side effects such as headaches, upper respiratory infections, nasopharyngitis, diarrhea, abdominal pain, nausea, constipation, muscle pain, limb pain, back pain, pruritus, thrombocytopenia, dizziness, indigestion, gastritis, weight loss, hypertension, hypernatremia, and erectile dysfunction may occur, so if symptoms are severe, you should consult a doctor. Severe joint pain or skin blistering may occur, so if these symptoms arise, treatment should be stopped immediately and a specialist should be consulted. It is recommended that women who are pregnant or breastfeeding do not take this medication, and safety in children and adolescents under 18 years of age has not been established. Elderly patients may have reduced kidney function, so dosage adjustments and kidney function tests are even more important. In cases of overdose, general emergency treatment should be provided, and blood dialysis may be necessary to remove this medication if needed. There are relatively few drug interactions, but caution should be exercised when used with specific medications under a doctor's guidance.

Serious side effects

• Hives
• severe swelling (angioedema)
• anaphylaxis
• chest tightness
• difficulty breathing
• cold sweat
• pallor
• severe rash
• blisters
• skin peeling

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• abdominal pain
• nausea
• constipation
• muscle pain
• limb pain
• back pain

This medication should be stored in a tight container to prevent exposure to air and moisture. It is best to maintain storage temperatures between 1 and 30 degrees Celsius. Doing so will help maintain the effectiveness of the medication and prevent degradation.

Appearance

Bright yellow-orange round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle