JanuaTin Tablet 50 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This drug is administered once daily at a dose of 100 mg for monotherapy or combination therapy and the maximum daily dose is 100 mg. In patients with renal impairment, mild and moderate renal impairment do not require dose adjustment. Patients with moderate renal impairment (eGFR between 30 and 45 mL/min/1.73 m2) are prescribed 50 mg once daily. Patients with severe renal impairment (eGFR between 15 and 30 mL/min/1.73 m2) are prescribed 25 mg once daily.

This drug can cause severe allergic reactions; if symptoms such as skin rash or difficulty breathing occur, discontinue use immediately and consult a doctor. Additionally, inflammation of the pancreas may occur, so if abdominal pain, vomiting, or nausea occurs, visit a hospital immediately. This drug should not be used in patients with type 1 diabetes or diabetic ketoacidosis. Patients with poor kidney function should adjust the dose of this drug and take it according to the physician's instructions. Hypoglycemia may occur during the use of this drug, especially when taken together with other diabetes medications such as insulin or sulfonylurea, so blood sugar levels should be monitored closely. Rarely, joint pain, skin rash, and vesicular skin diseases may occur; if these symptoms appear, inform a doctor and seek treatment. It is advisable for women who are pregnant or breastfeeding not to take this drug, and safety and efficacy have not been established in children under 18 years of age. Elderly patients may have reduced kidney function, so regular kidney function tests should be conducted before and during treatment. In case of overdose, general emergency treatment will be provided, and this drug can be removed via dialysis if necessary. This drug interacts minimally with other medications, but it should be discussed with a doctor when taking specific drugs.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor (anaphylaxis and other severe hypersensitivity reactions), severe rash with high fever, blisters, skin shedding, pain in oral/eye mucosa (Stevens-Johnson syndrome and other severe skin adverse reactions), severe respiratory issues, jaundice (yellowing of skin or eyes), extreme lethargy (liver abnormalities), sudden and severe headache, thunderclap headache,

Mild side effects

• Nasopharyngitis
• upper respiratory infection
• headache
• nausea
• diarrhea
• constipation
• myalgia
• limb pain
• back pain
• dyspepsia

This drug should be stored in a tightly sealed container to prevent air exposure and kept at a cool room temperature between 1 and 30 degrees Celsius. Storing it this way can help maintain the effectiveness of the medication for a long time.

Appearance

Bright yellow-orange round film-coated tablets

Package unit

100 tablets/bottle, 30 tablets/bottle