Glicita Tablet 25mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

The usual dose of this medication is 100 mg once daily for either monotherapy or combination therapy, with a maximum daily dosage of 100 mg. It can be taken regardless of meals. For patients with renal impairment, dosage adjustment is necessary according to kidney function. - Mild renal impairment (eGFR ≥ 60 and < 90 mL/min/1.73 m2): No dosage adjustment required - Moderate renal impairment (eGFR ≥ 45 and < 60 mL/min/1.73 m2): Dosage adjustment is needed.

This medication can cause allergic reactions; if symptoms such as skin rash or difficulty breathing occur, discontinue use immediately and consult a physician. If severe abdominal pain, a symptom of pancreatitis, occurs while taking this medication, notify healthcare personnel immediately, and discontinue medication if necessary. Patients with type 1 diabetes or diabetic ketoacidosis should not use this medication. Patients with impaired renal function need dosage adjustment of this medication, so regular kidney function tests should be performed, and it should be taken according to physician’s instructions. There is a risk of hypoglycemia when taking this medication, especially when used in combination with insulin or sulfonylureas; blood sugar levels should be monitored frequently, and symptoms should be carefully observed. If severe joint pain or blisters on the skin occur, notify a physician immediately and discontinue medication. Pregnant or breastfeeding women are advised to avoid using this medication, and safety and effectiveness in children have not been established. Elderly patients may require dosage adjustments and regular kidney function tests due to potentially reduced renal function. In cases of overdose, seek medical attention immediately because this medication can be partially removed by dialysis. This medication has fewer drug interactions; however, when used in combination with digoxin, blood concentration levels should be monitored. If any abnormal symptoms occur while taking this medication, consult healthcare personnel immediately.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing (anaphylaxis), cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in the mouth/eyes (Stevens-Johnson syndrome), acute pancreatitis, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache.

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• nausea
• abdominal pain
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius to ensure the prolonged effectiveness of the drug.

Appearance

Pink, round double-convex film-coated tablets

Package unit

28 tablets/box [14 tablets/PTPX2]