Jadiflozin 25mg (Empagliflozin)

Adult dose

The recommended dosage of this medication for monotherapy and additional combination therapy with other glucose-lowering agents such as insulin is 10 mg once daily. If 10 mg is well tolerated and additional blood glucose control is needed, it can be increased to 25 mg once daily. This medication can be taken with or without food, and the tablet should be swallowed whole. If a dose is missed, take it as soon as remembered, and do not take two doses in one day.

This medication should not be used in patients who are allergic to the active ingredient. This medication may be dangerous if administered to patients with type 1 diabetes or diabetic ketoacidosis. Patients with severely impaired kidney function, end-stage renal disease, or those on dialysis should not use this medication. This medication contains lactose and should not be administered to patients with genetic problems such as lactose intolerance, galactose intolerance, lactose deficiency, or glucose-galactose malabsorption. Patients with reduced kidney function require dose adjustment when taking this medication, and it should be discontinued if kidney function falls below a certain level. The use of this medication is not recommended in patients with severe heart failure and should be administered carefully in mild cases. If used in combination with insulin or insulin secretagogues, there may be an increased risk of hypoglycemia, so dose adjustments of these medications may be necessary. While taking this medication, patients may experience side effects such as hypoglycemia, genital infections, urinary tract infections, increased urination, and reduced fluid volume, so caution is advised. Severe metabolic abnormalities such as ketoacidosis may occur, so if symptoms like vomiting, abdominal pain, or difficulty breathing arise, immediate consultation with medical personnel is required. Elderly patients or those at risk of fluid volume depletion should be cautious of dehydration and hypotension, and fluid status should be checked regularly. This medication can cause serious urinary infections such as urosepsis and pyelonephritis, so prompt treatment is necessary if infection symptoms arise. Pregnant women are advised not to take this medication, and it should be avoided during breastfeeding as well. The safety and efficacy of this medication in children under 18 years of age have not been established, so it should not be used in this population. Although no specific toxic symptoms have been reported with overdose, appropriate treatment is necessary depending on the clinical condition. This medication may cause mild effects when driving or operating machinery, so caution should be exercised, especially if there is a risk of hypoglycemia. Additionally, diabetic patients should pay attention to foot care and regularly check their feet to reduce the risk of limb amputation. If pain, swelling, or redness appears around the perineum, immediate notification to medical personnel and appropriate treatment should be sought.

Serious side effects

• Hives
• angioedema
• ketoacidosis
• urosepsis and pyelonephritis
• perineal necrosis
• deep vein thrombosis
• sudden and severe headache
• stroke
• intracranial aneurysm
• visual disturbances

Mild side effects

• Hypoglycemia
• vulvovaginitis
• balanitis
• and other genital infections
• itching
• rash
• increased urination
• increased serum creatinine
• decreased glomerular filtration rate
• thirst

This medication must be stored in a tightly sealed container to protect it from air and moisture. It is best to store it at room temperature between 1 and 30 degrees Celsius.

Appearance

Light yellow, biconvex, oval film-coated tablets

Package unit

30 tablets/bottle