Medication info
Atorva MZ Tablets 10/10 mg

Atorva MZ Tablets 10/10 mg

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium Trihydrate›10.85mg / 1 tabletEzetimibe›10mg / 1 tablet
Manufacturer / importer
(주)마더스제약
Appearance
White, rectangular film-coated tablets
Packaging
30 tablets/Alu-Alu[(10 tablets/Alu-Alu×3)]
Approval status
Active

MFDS item code 202101650 · Approved 2021.02.18 · Insurance code 622804530

Summary

Main use
Improvement of cholesterol and lipid levels in hypercholesterolemia (primary, homozygous familial) and dyslipidemia
Who uses it
Adults
Adult dosage
This medication is administered once daily, regardless of meals. For primary hypercholesterolemia, the dosage ranges from 10/10 mg to 10/80 mg daily, with an initial recommended dose of 10/10 mg or 10/20 mg daily. If a greater reduction in LDL-cholesterol is required, an initial dose of 10/40 mg daily is recommended. Blood lipid levels should be checked at intervals of more than 2 weeks after starting therapy or making dose adjustments.

Ingredients

Manufacturer
(주)마더스제약

Efficacy & effects

Improvement of cholesterol and lipid levels in hypercholesterolemia (primary, homozygous familial) and dyslipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • dyslipidemia
  • hypercholesterolemia
  • atherosclerotic vascular disease
View approved original text

This medication helps to lower elevated total cholesterol, LDL-cholesterol, Apo B protein, triglycerides, and non-HDL-cholesterol levels while raising HDL-cholesterol in patients with primary hypercholesterolemia and mixed dyslipidemia. It can effectively manage blood cholesterol levels in patients with homozygous familial hypercholesterolemia when used alone or in combination with other therapies. This medication is particularly useful when dietary adjustments and non-drug treatments are insufficient and improves health by managing lipids in patients at high risk of vascular disease. It is important to identify secondary causes like diabetes and hypothyroidism before treatment and take necessary measures. Regular tests of lipid levels can enable treatment safely and effectively. This medication is used to improve health problems associated with hypercholesterolemia.

Dosage and Administration

Adult dosage

This medication is administered once daily, regardless of meals. For primary hypercholesterolemia, the dosage ranges from 10/10 mg to 10/80 mg daily, with an initial recommended dose of 10/10 mg or 10/20 mg daily. If a greater reduction in LDL-cholesterol is required, an initial dose of 10/40 mg daily is recommended. Blood lipid levels should be checked at intervals of more than 2 weeks after starting therapy or making dose adjustments.

Precautions

This medication can cause serious muscle problems, so patients should notify their physician immediately if symptoms like muscle pain, cramps, or weakness occur. Especially in cases of impaired kidney function, severe infections, major surgeries, or trauma, it may be necessary to temporarily discontinue or halt this medication. Patients allergic to the ingredients or with severely impaired liver function, those with muscle diseases, pregnant or nursing women should not take this medication. Patients with certain liver diseases or significantly elevated liver enzyme levels should also avoid using this medication. Caution is advised for patients with a history of alcohol addiction or liver disease, impaired kidney function, hypothyroidism, or elderly patients, as they are at higher risk for muscle problems. As this medication can interact with others, especially those affecting liver metabolism or muscles, patients should consult their physician when taking other medications. Liver function abnormalities can occur, so routine checks of liver function test results are necessary, and if symptoms of liver damage arise, use should be discontinued immediately. Blood sugar levels may increase during the use of this medication, and patients at risk for diabetes should monitor their blood sugar regularly. Women who are pregnant or may become pregnant should employ adequate contraception while taking this medication and discontinue use immediately upon confirmation of pregnancy. It is also advisable for nursing women to avoid this medication, as there is a possibility it may be excreted in breast milk. Dizziness or drowsiness may occur, so caution is necessary when driving or operating machinery. The safety and effectiveness of this medication have not been established in children, so it is not recommended. In case of overdose, there is no specific antidote, so symptomatic treatment and supportive care should be pursued, along with monitoring liver function and muscle enzyme levels.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, and urinary changes.

Mild side effects

  • Muscle pain
  • abdominal pain
  • dizziness
  • cough
  • nausea
  • diarrhea
  • joint pain
  • muscle weakness
  • musculoskeletal pain
  • hyperkalemia
Show 25 more
  • bronchitis
  • sinusitis
  • flushing
  • nasopharyngitis
  • constipation
  • dyspepsia
  • throat and laryngeal pain
  • nosebleed
  • insomnia
  • nightmares
  • sensory disturbances
  • taste disturbances
  • memory loss
  • peripheral neuropathy
  • itching
  • rash
  • hair loss
  • angioedema
  • skin rash
  • urticaria
  • dry skin
  • urticaria
  • bronchiolitis
  • dental abscess
  • and more.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air and moisture. Additionally, it should be kept at room temperature, between 1 and 30 degrees Celsius, to maintain its efficacy and safety.

Appearance and packaging

Appearance

White, rectangular film-coated tablets

Package unit

30 tablets/Alu-Alu[(10 tablets/Alu-Alu×3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.