Atoel Jet Tablets 10/40 mg

Adult dosage

This medication is taken once daily regardless of meals. For primary hypercholesterolemia, the dosing range is 10/10 mg to 10/80 mg per day, and a starting dose of 10/10 mg or 10/20 mg is recommended. For patients requiring a more significant (>55%) reduction in LDL cholesterol, a starting dose of 10/40 mg per day is recommended. Recommended dosage for patients with homozygous familial hypercholesterolemia.

This medication has been reported to cause rare side effects such as rhabdomyolysis, which can lead to severe muscle injury, and should be temporarily withheld or discontinued in patients who display serious myopathy symptoms or are at high risk for renal issues. Patients with allergies to any components of this medication, severely impaired liver function or active liver disease, existing muscle disorders, pregnant women or those likely to become pregnant, nursing women, or patients taking certain antiviral medications should not take this medication. Patients with a history of alcoholism or liver disease, impaired renal function, hypothyroidism, older adults, and those on certain medications should use this medication with caution and consult a physician immediately if muscle-related adverse symptoms occur. Adverse effects such as muscle pain, abdominal pain, and elevation of liver enzymes can occur during the use of this medication, and patients should inform their doctor if symptoms are severe or persist. Additionally, as this medication may affect liver function, regular liver function tests should be conducted before and during treatment, and administration should be immediately stopped if signs of liver damage appear. This medication may elevate blood sugar levels; however, the benefits of reducing cardiovascular disease risk are more significant, thus patients who require blood sugar management should discuss use with their healthcare provider. This medication should not be taken during pregnancy or breastfeeding, and women of childbearing age should use appropriate contraception. The safety and efficacy of this medication have not been established in children and is therefore not recommended. Older adults are at increased risk for muscle-related side effects and should exercise caution when taking this medication. This medication has many potential interactions with other drugs, particularly certain antibiotics, antivirals, antifungals, antihypertensives, and antihyperglycemic agents, thus dose adjustments and monitoring under a physician's guidance are necessary when taken together. There are no specific antidotes for overdose, so treatment should be symptomatic and managed through monitoring liver function and muscle enzyme levels. Dizziness or muscle aches may occur, thus caution is necessary when driving or operating machinery. Lastly, store this medication out of the reach of children and do not transfer it to other containers for safety.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucous membranes, shortness of breath or difficulty breathing, asthma attacks, breathing abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), severe general lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• vomiting
• joint pain
• muscle weakness
• musculoskeletal pain

This medication should be stored in a tightly sealed container to protect it from air and moisture. The storage temperature should ideally be maintained at room temperature between 1°C and 30°C. Proper storage will help preserve the medication's efficacy and safety over a longer period.

Appearance

White rectangular film-coated tablets

Package unit

For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle