Medication info
Hantojet Tablet 10/20 Milligrams

Hantojet Tablet 10/20 Milligrams

Prescription medicationTablet
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›21.7mg / 1 tablet
Manufacturer / importer
한올바이오파마(주)
Appearance
White, rectangular film-coated tablet
Packaging
30 tablets/box [10 tablets/PTP packaging (Alu-Alu)x3]
Approval status
Active

MFDS item code 202101583 · Approved 2021.02.18 · Insurance code 655605310

Summary

Main use
Improvement of lipid levels by reducing cholesterol and LDL in hypercholesterolemia (primary, familial) and dyslipidemia and increasing HDL.
Who uses it
Adults
Adult dosage
This drug is administered once daily regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10mg to 10/80mg daily, with an initial recommended dosage of 10/10mg or 10/20mg daily. If a greater reduction in LDL-C is required, an initial dose of 10/40mg daily is recommended. For patients with homozygous familial hypercholesterolemia, the recommended dosage is 10/40mg daily.

Ingredients

Manufacturer
한올바이오파마(주)

Efficacy & effects

Improvement of lipid levels by reducing cholesterol and LDL in hypercholesterolemia (primary, familial) and dyslipidemia and increasing HDL.

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • dyslipidemia
  • atherosclerotic vascular disease caused by hypercholesterolemia.
View approved original text

This drug is used as an adjunct to dietary therapy to lower elevated total cholesterol, LDL-C, Apo B, triglycerides, and non-HDL cholesterol levels, and to increase HDL-C levels in patients with primary hypercholesterolemia and mixed dyslipidemia. It may also be administered as an adjunctive treatment for patients with homozygous familial hypercholesterolemia, in combination with existing therapies or when other treatments are ineffective. This drug is used alongside an appropriate diet and non-drug measures, and secondary causes of dyslipidemia must be confirmed and treated for it to be effective. It is safe to use as a lipid-lowering agent in patients at high risk for cardiovascular disease, and blood lipid levels should be monitored before and after therapy. This drug helps improve cardiovascular health by regulating lipid levels.

Dosage and Administration

Adult dosage

This drug is administered once daily regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10mg to 10/80mg daily, with an initial recommended dosage of 10/10mg or 10/20mg daily. If a greater reduction in LDL-C is required, an initial dose of 10/40mg daily is recommended. For patients with homozygous familial hypercholesterolemia, the recommended dosage is 10/40mg daily.

Precautions

This drug can pose a risk of muscle-related adverse effects, so patients must inform their doctor immediately if they experience severe muscle pain or weakness symptoms. Additionally, patients with renal function issues due to severe infections, surgeries, trauma, etc., may need to temporarily interrupt or adjust the dosage of this drug. This drug should not be administered to patients allergic to any of its components, those with severe liver impairment, muscle diseases, or women who are pregnant or breastfeeding. Patients with a history of alcohol dependence or liver disease, those with impaired renal function, hypothyroidism, the elderly, and others at high risk of muscle abnormalities should use this medication with caution. Combining this drug with certain other medications may increase the risk of muscle damage, so patients must consult with their doctor or pharmacist regarding any co-administered medications. Periodic liver function tests are necessary if liver function abnormalities are present, and if symptoms of liver damage (e.g., nausea, vomiting, fatigue) occur, patients should immediately discontinue use and consult medical personnel. Blood sugar levels may fluctuate during treatment, so diabetic patients must carefully manage their blood sugar levels, and women of childbearing age should use appropriate contraception. Caution should be exercised while driving or operating machinery due to the potential for dizziness. This drug is not recommended for children as its safety and efficacy in this population have not been established, and it should be used cautiously in the elderly due to the risk of muscle abnormalities. In case of overdose, there is no specific antidote, and treatment should be symptomatic along with supportive therapy, and monitoring of liver function and muscle enzyme levels is required.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), severe allergic reactions, chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound fatigue, liver abnormalities (jaundice), sudden and severe.

Mild side effects

  • Muscle pain
  • abdominal pain
  • elevated liver enzymes
  • dizziness
  • cough
  • nausea
  • diarrhea
  • joint pain
  • muscle weakness
  • joint swelling
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  • muscle cramps
  • throat pain
  • muscle fatigue
  • headache
  • fatigue
  • constipation
  • hyperkalemia
  • bronchitis
  • sinusitis
  • flushing
  • vomiting
  • dyspepsia
  • pharyngitis
  • edema
  • weakness
  • malaise
  • chest pain
  • fever
  • insomnia
  • nightmares
  • sensory disturbance
  • taste disturbance
  • amnesia
  • peripheral neuropathy
  • thrombocytopenia
  • hepatitis
  • blurred vision
  • tinnitus.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. It is recommended to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature to preserve its efficacy.

Appearance and packaging

Appearance

White, rectangular film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP packaging (Alu-Alu)x3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.