Medication info
Aitojet Tablet 10/10 mg

Aitojet Tablet 10/10 mg

Prescription medicationTablet
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›10.85mg / 1 tablet
Manufacturer / importer
아이큐어(주)
Appearance
White oval film-coated tablet
Packaging
30 tablets/box[(10 tablets/PTP packaging (Alu-Alu)x3)], 30 tablets/bottle
Approval status
Active

MFDS item code 202101561 · Approved 2021.02.18 · Insurance code 674402400

Summary

Main use
Improvement of hypercholesterolemia and dyslipidemia (total cholesterol, LDL-C, etc.)
Who uses it
Adults
Adult dosage
This medication is administered once daily, regardless of meals. The dosage should be adjusted based on the patient's baseline LDL cholesterol, target treatment levels, and response to the medication. The dosage range for primary hypercholesterolemia is 10/10mg to 10/80mg once daily, and the recommended initial dose is either 10/10mg or 10/20mg once daily. If a greater reduction in LDL cholesterol is needed, the initial dose may be 10/40mg once daily. Start administration

Ingredients

Manufacturer
아이큐어(주)

Efficacy & effects

Improvement of hypercholesterolemia and dyslipidemia (total cholesterol, LDL-C, etc.)

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • elevated total cholesterol
  • elevated LDL cholesterol
  • elevated apo B protein
  • elevated triglycerides
  • elevated non-HDL cholesterol
View approved original text

This medicine is used as an adjunct to dietary therapy to lower elevated total cholesterol, LDL cholesterol, apo B protein, triglycerides, and non-HDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia, and to raise levels of good cholesterol (HDL cholesterol). It is also administered as an adjunctive therapy when other lipid-lowering treatments are insufficient in patients with homozygous familial hypercholesterolemia. This medication is used along with appropriate dietary therapy in patients at high risk of cardiovascular disease, and it is also important to treat other secondary causes. Before administration, blood lipid levels should be checked, and if necessary, accurate LDL concentrations should be confirmed by ultracentrifugation. Overall, this drug helps to improve dyslipidemia and reduce the risk of atherosclerotic vascular disease.

Dosage and Administration

Adult dosage

This medication is administered once daily, regardless of meals. The dosage should be adjusted based on the patient's baseline LDL cholesterol, target treatment levels, and response to the medication. The dosage range for primary hypercholesterolemia is 10/10mg to 10/80mg once daily, and the recommended initial dose is either 10/10mg or 10/20mg once daily. If a greater reduction in LDL cholesterol is needed, the initial dose may be 10/40mg once daily. Start administration

Precautions

This medication can cause serious muscle problems, so if symptoms of muscle pain or weakness occur, you must inform your doctor immediately. Patients with weakened kidneys due to severe infection, low blood pressure, major surgery or trauma, or endocrine disorders may need to temporarily withdraw or stop this medication. This medicine should not be used in individuals with certain diseases, such as those with liver disease or muscle disorders, pregnant or breastfeeding women, or those taking certain medications. Additionally, individuals with genetic disorders such as lactose intolerance should not take this medication. Patients who are alcoholics, have poor liver function, have weakened kidney function, have hypothyroidism, have a family history of muscle disorders, and the elderly should use this medication cautiously, and discuss the possibility of muscle problems with their doctor. Regular liver function and muscle-related tests should be performed while taking this medicine, and if symptoms such as liver dysfunction, muscle pain, or muscle weakness occur, immediate consultation with medical personnel is essential. Furthermore, if taken with other medications, the risk of side effects due to drug interactions may increase, so consultation with a doctor or pharmacist is necessary. This medication should not be taken by pregnant women or those who might become pregnant and adequate contraception must be used during treatment. Breastfeeding women should also avoid taking this medicine. Special precautions are needed for the elderly and children, and in the case of children, its safety and efficacy have not been established so it is not recommended. In cases of overdose, there are no specific antidotes, and treatment should be symptomatic while monitoring liver function and muscle enzyme levels. Finally, this medication should be kept out of reach of children, and it is advisable not to transfer it to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, breathing abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, vision abnormalities, paralysis, urination

Mild side effects

  • Dizziness
  • cough
  • abdominal pain
  • nausea
  • diarrhea
  • muscle pain
  • joint pain
  • musculoskeletal pain
  • hyperkalemia
  • bronchitis
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  • sinusitis
  • flushing
  • increased ALT
  • increased AST
  • fatigue
  • malaise
  • chest pain
  • chest discomfort
  • edema
  • weakness
  • vasomotor edema
  • facial edema
  • fever
  • headache
  • hypoglycemia
  • hyperglycemia
  • weight gain
  • loss of appetite
  • constipation
  • abdominal bloating
  • indigestion
  • belching
  • pancreatitis
  • throat and laryngeal pain
  • nosebleed
  • insomnia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. It is important to maintain the storage temperature between 1 degree and 30 degrees Celsius at room temperature. This will help to preserve the effectiveness of the medication for a long time.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/box[(10 tablets/PTP packaging (Alu-Alu)x3)], 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.