Atovast Jet Tablets 10/40 Milligrams

Adult dosage

This medication is taken once daily, regardless of meals. For primary hypercholesterolemia, the dose range is 10/10 mg to 10/80 mg daily. A starting dose of 10/10 mg or 10/20 mg daily is recommended. For patients requiring a more significant reduction in LDL-cholesterol (greater than 55%), a starting dose of 10/40 mg daily is recommended. After initiation of treatment or dose adjustment, cholesterol and lipid levels should be monitored after intervals of more than 2 weeks.

This medication has been rarely associated with a serious side effect called rhabdomyolysis, which can result in muscle tissue damage and kidney dysfunction. Therefore, immediate consultation with a physician is necessary if severe muscle pain or weakness symptoms appear, and the use of this medication may need to be temporarily stopped if there are risk factors such as severe infection, hypotension, major surgery or trauma, or uncontrolled seizures. This medication should not be administered to patients with allergies to the active ingredient or other excipients, those with severe liver dysfunction, muscle disorders, women who are pregnant or may become pregnant, nursing mothers, and patients taking certain other medications. Caution should be exercised when administering this medication to patients with a history of alcohol abuse or liver disease, those with severe liver dysfunction, renal impairment, hypothyroidism, a history of genetic muscle disorders, and elderly patients over 70 years old who are at higher risk of muscle damage. Additionally, this medication contains lactose and should not be taken by patients with lactose intolerance or related genetic diseases. During treatment with this medication, if symptoms like muscle pain, weakness, muscle cramps, fatigue, or muscle pain associated with fever develop, immediate notification to a physician is required, and blood tests may be necessary to check for muscle damage. As abnormal liver function may occur, liver function tests should be conducted before and during treatment, and treatment should be stopped if liver damage symptoms arise. This medication may slightly elevate blood sugar levels; however, the cardiovascular disease prevention benefits generally outweigh this concern when considered as a treatment rationale. Women who are pregnant or may become pregnant should not take this medication, and appropriate contraception should be used while on treatment. Nursing mothers are also advised not to take this medication. Safety and efficacy have not been established in children, so it is not recommended for pediatric use. When administering to the elderly, caution should be exercised due to the risk of muscle damage, but no specific dose adjustment is necessary. This medication can interact with several drugs, so patients taking other medications should inform their physician or pharmacist, as dose adjustment or caution may be required when taken concomitantly with certain drugs. Caution is also advised as dizziness may occur when driving or operating machinery. In cases of overdose, there is no specific antidote, and treatment should focus on symptom management and supportive care, while monitoring liver function and potential muscle damage. This medication should be kept out of reach of children, and it is advisable not to transfer it to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, mucosal pain in mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress with cough and fever, jaundice (yellowing of the skin or eyes), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urine changes.

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain

This medication can be sensitive to air or moisture, thus it should be stored in a tightly sealed container. A storage temperature between 1 to 30 degrees Celsius at room temperature is recommended. This helps maintain the medication's effectiveness for a prolonged period.

Appearance

White or whitish elongated film-coated tablets

Package unit

30 tablets/box [(10 tablets/Alu-Alu x 3)]