Igliptin Tablet 50 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg for both monotherapy and combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment, dose adjustments are necessary based on renal function. Mild and some moderate renal impairment patients do not require dose adjustments. However, for moderate renal impairment (glomerular filtration rate of 30-45 mL/min/1.73 m2), the dose is 50 mg once daily. Severe renal impairment

This medication can cause severe allergic reactions, so if symptoms such as skin rash or difficulty breathing occur, discontinue use immediately and consult a doctor. During treatment with this medication, if symptoms of pancreatitis such as abdominal pain, vomiting, or severe abdominal pain occur, notify medical personnel immediately. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, nor in individuals who are allergic to this medication or its components. Patients with reduced renal function should have their dosage adjusted, and it is recommended to conduct regular kidney function tests. Patients may experience side effects such as cold symptoms, headache, indigestion, or diarrhea while taking this medication, and if symptoms are severe, consult a doctor. Caution is advised when taking this medication in conjunction with other hypoglycemic agents such as insulin or sulfonylureas, as the risk of hypoglycemia may increase; regular monitoring of blood glucose levels and dosage adjustment may be necessary. If symptoms of severe joint pain or skin blistering occur, discontinue this medication immediately and seek professional treatment. The use of this medication in pregnant or nursing women is not recommended, and safety and effectiveness have not been established in individuals under 18 years of age. In cases of overdose, seek appropriate medical treatment immediately, as this medication can be partially removed by hemodialysis. This drug has low interaction with other medications, but patients should inform their physician of any concurrent medications, especially when taken with cyclosporine or digoxin caution is needed. Elderly patients may have a risk of decreased renal function, so dosage adjustments and regular kidney function tests are necessary.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin shedding, mucosal pain in the mouth/eyes, Stevens-Johnson syndrome, severe allergic reactions, severe skin adverse reactions, difficulty or shortness of breath, asthma attack, respiratory abnormalities accompanied by coughing and fever, jaundice (yellowing of the skin or eyes), systemic lethargy, liver abnormalities (jaundice)

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• diarrhea
• nausea
• abdominal pain
• constipation
• vomiting
• myalgia
• limb pain

This medication should be stored in a tightly closed container that prevents air access, and it is best to keep it at a temperature between 1 degree and 30 degrees Celsius. Proper storage helps maintain the drug's effectiveness for a longer duration.

Appearance

Light apricot-colored, round, biconvex film-coated tablet

Package unit

PTP - 28 tablets/PTP [(14 tablets/PTP x 2)]