Medication info
Candero One Tablet 5/8 mg (Rosuvastatin, Candesartan)

Candero One Tablet 5/8 mg (Rosuvastatin, Candesartan)

Prescription medicationTablet경구
Ingredient · strength
Rosuvastatin Calcium›5.2mg / 1 tabletCandesartan Cilexetil›8mg / 1 tablet
Manufacturer / importer
하나제약(주)
Appearance
Pink, round, film-coated tablets
Packaging
30 tablets/box [(10 tablets/PTP X 3)]
Approval status
Active

MFDS item code 202008716 · Approved 2020.12.11 · Insurance code 657808170

Summary

Main use
(Hypertension, Heart Failure) treatment and (Hyperlipidemia, Cardiovascular disease risk) improvement
Who takes it
Adults · Children
Adult dose
Candesartan cilexetil: 1. Essential Hypertension - The recommended initial and maintenance dose is to take 8 to 16 mg orally once a day. - If blood pressure control is inadequate after 4 weeks at a dose of 16 mg, the dose may be increased to a maximum of 32 mg once a day. - For patients with reduced intravascular effective blood volume or renal impairment: the initial dose should be 4 mg. - For patients with liver impairment: start with 2 mg once daily for mild to moderate cases, adjusting the dose as necessary.
Child dose
Safety and efficacy in patients under 18 years have not been established, hence not recommended for administration.

Ingredients

Manufacturer
하나제약(주)

Efficacy & effects

(Hypertension, Heart Failure) treatment and (Hyperlipidemia, Cardiovascular disease risk) improvement

  • Essential hypertension
  • left ventricular systolic dysfunction
  • hyperlipidemia
  • heterozygous familial hypercholesterolemia
  • mixed hyperlipidemia
  • homozygous familial hypercholesterolemia
  • dysbetalipoproteinemia
  • increased high-sensitivity C-reactive protein
  • hypertension
  • low HDL-cholesterol levels
  • smoking
  • family history of premature coronary artery disease
View approved original text

This medication is used for patients who need to take both Candesartan cilexetil and Rosuvastatin. Candesartan cilexetil is primarily used for essential hypertension patients and those with heart failure who have decreased left ventricular systolic function, particularly when additional therapy with ACE inhibitors is needed or when they have poor tolerance. Rosuvastatin is used as an adjunct to dietary therapy for patients with hyperlipidemia, especially for heterozygous and homozygous familial hypercholesterolemia and other forms of hyperlipidemia. It also helps lower cholesterol levels in patients with hyperlipidemia, slow the progression of atherosclerosis, and reduce the risk of cardiovascular diseases. Specifically, it contributes to lowering the risks of stroke, myocardial infarction, and revascularization in high-risk patients with cardiovascular disease risk factors. Thus, both ingredients are effective for managing blood pressure and cholesterol and improving cardiovascular health.

How to take

Adult dose

Candesartan cilexetil: 1. Essential Hypertension - The recommended initial and maintenance dose is to take 8 to 16 mg orally once a day. - If blood pressure control is inadequate after 4 weeks at a dose of 16 mg, the dose may be increased to a maximum of 32 mg once a day. - For patients with reduced intravascular effective blood volume or renal impairment: the initial dose should be 4 mg. - For patients with liver impairment: start with 2 mg once daily for mild to moderate cases, adjusting the dose as necessary.

Child dose

Safety and efficacy in patients under 18 years have not been established, hence not recommended for administration.

Precautions

This medication can cause serious harm to the fetus, especially after the second trimester of pregnancy, so it should be discontinued immediately if pregnancy is confirmed. It should not be administered to patients with allergic reactions to this drug, severely impaired liver function, muscle disorders, severe kidney disease, etc. Patients with low blood pressure, weak kidney function, elderly individuals, and those with hyperkalemia should be more cautious when using this medication, requiring regular blood tests and physical assessments. Consult a doctor immediately if muscle pain or weakness occurs, and medication may need to be discontinued in severe cases. If liver dysfunction is suspected, liver enzyme levels should be checked, and if abnormalities exist, discontinuation of the drug is necessary. Combining with other antihypertensive agents or specific medications may increase the risk of side effects, so it is essential to inform healthcare professionals about any concurrent medications. Be cautious when driving or operating machinery as dizziness or drowsiness may occur. Keep out of reach of children, and it’s safe not to transfer the medication to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe malaise, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urinary output

Mild side effects

  • Headache
  • dizziness
  • orthostatic dizziness
  • nasopharyngitis
  • papules
  • local infections
  • periodontitis
  • fatigue
  • inflammation
  • foreign body sensation
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  • itching
  • generalized pruritus
  • dermatitis
  • musculoskeletal pain
  • neck pain
  • limb pain
  • photophobia
  • dyspepsia
  • nausea
  • increased blood glucose
  • decreased sodium levels
  • hand fractures
  • hypoglycemia
  • nephrolithiasis
  • cough
  • dental extraction
  • weight gain
  • facial edema
  • dry mouth
  • sleep disturbances
  • decreased libido
  • forgetfulness
  • anorexia
  • increased appetite
  • tinnitus
  • altered taste

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. It is important to maintain storage temperatures between 1 degree and 30 degrees Celsius at room temperature to preserve its effectiveness and safety over time.

Appearance and packaging

Appearance

Pink, round, film-coated tablets

Package unit

30 tablets/box [(10 tablets/PTP X 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.