STOPIHEMOSTATIC

Adult dosage

1. Thrombin freeze-dried powder 5000 units Dissolve the powder in saline to prepare a solution (50～1,000 units/mL of thrombin) and spray, instill, or apply the powder directly to the site of local bleeding. Adjust dosage according to the bleeding site and severity. 2. Collagen absorbable wound dressing - Cut to the appropriate size for the treatment area. - Up to 3 pieces can be used based on a 10x10cm standard, considering the patient's weight and total amount of gentamicin sulfate.

This drug is used topically to assist with blood coagulation. However, it must never be injected intravenously, subcutaneously, or intramuscularly. If it enters the bloodstream, it can cause serious complications due to coagulation. Patients who have had an allergic reaction to this drug or are taking specific pro-coagulants or anti-fibrinolytics should not use it. Caution is advised for patients with severe liver dysfunction or abnormal blood coagulation issues, as well as for pregnant women or women of childbearing potential. There may be rare but serious allergic reactions such as dyspnea or hypotension; therefore, symptoms should be carefully monitored. Additionally, this drug may affect blood coagulation, leading to bleeding or thrombosis, so use should be discontinued immediately if abnormal symptoms occur. This drug should not be used in combination with other coagulants or anti-fibrinolytics as it may increase the risk of thrombosis. When used in solution form, care must be taken to ensure it does not enter the bloodstream, and it should be used immediately after preparation. The safety for pregnant women or children has not been sufficiently confirmed, so it should be used cautiously only in special cases.

Serious side effects

Hives, swelling, dyspnea, hypotension, abnormal bleeding, shock symptoms, cyanosis, hypotension, neurotoxicity (dizziness, tinnitus, hearing loss), decreased urination, symptoms related to kidney impairment (renal failure)

Mild side effects

• Rash
• fever
• itching
• nausea
• vomiting
• headache
• skin whitening
• localized redness
• flushing
• inflammation

This drug should be stored in a sealed container to protect it from air and is best kept at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's efficacy.

Appearance

A kit consisting of BM Thrombin freeze-dried powder 5000 units (1 vial each of drug and diluent), collagen absorbable wound dressing, universal catheter cannula, syringe, and injection needle.

Package unit

1 kit/kit