Sitalen 100 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

The medication is administered once daily at a dose of 100 mg for monotherapy or combination therapy with a maximum daily dose of 100 mg. It can be taken regardless of meals. In patients with renal impairment, dosage adjustment is necessary based on kidney function. - Mild to moderate renal impairment (eGFR 45 to <90): No dosage adjustment is needed. - Moderate renal impairment (eGFR 30 to <45): Administer 50 mg once daily.

This medication can cause severe allergic reactions; if symptoms such as skin rash or difficulty breathing occur, discontinue use immediately and consult a doctor. This medication can cause a serious pancreatic inflammation called pancreatitis, so if symptoms such as abdominal pain or vomiting occur while taking it, notify medical staff promptly. Do not use in patients with type 1 diabetes or diabetic ketoacidosis, and also should not be administered in cases of allergy to the drug or its components. Patients with impaired kidney function may have difficulty excreting this medication, so dosage adjustments are necessary according to kidney function, and use must be done cautiously. Hypoglycemic symptoms can occur while taking this medication, especially when used together with insulin or sulfonylurea, so blood sugar levels should be checked frequently and hypoglycemia should be monitored. This medication may cause side effects such as upper respiratory infections, headaches, indigestion, and diarrhea, so if symptoms persist or worsen, consult with medical staff. It is advisable for pregnant or breastfeeding women not to use this medication, and safety and efficacy have not been established for children or adolescents under 18 years of age. Elderly patients should be assessed for potential kidney function decline before administration, and dosage adjustment may be necessary. In case of overdose, immediately visit a medical facility for appropriate treatment, and blood dialysis may be performed based on medical judgment as some may be removed during dialysis. This medication may have interactions with other hypoglycemic agents or specific medications, so all medications being taken should be reported to the medical staff.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe skin reactions (such as Stevens-Johnson syndrome), shortness of breath or difficulty breathing, asthma attacks, cough and breathing abnormalities accompanied by fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache

Mild side effects

• Nasopharyngitis
• upper respiratory infection
• headache
• diarrhea
• abdominal pain
• nausea
• constipation
• muscle pain
• limb pain
• back pain

This medication should be stored in a sealed container to prevent air exposure and kept at a temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the medication for a longer period.

Appearance

Light orange, round, double convex film-coated tablets

Package unit

30 tablets/box [(10 tablets/PTP x 3)]