Lavana Tablet 20 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcer and duodenal ulcer: Administer 10 mg orally once a day, with the possibility to increase to 20 mg once a day based on symptoms. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If not resolved after 8 weeks of proton pump inhibitor (PPI) treatment, an additional 8 weeks of 10 mg or 20 mg twice daily may be given, with a maximum of 20 mg once daily.

This medication should not be used in patients who have had allergic reactions or hypersensitivity to specific components or benzimidazole derivatives. Additionally, caution is required for patients allergic to penicillin-based antibiotics or macrolide antibiotics, especially when used in combination for Helicobacter pylori eradication treatment. Patients taking drugs related to certain heart diseases, those taking atazanavir or rilpivirine, and women who are pregnant or breastfeeding should not use this medication for safety. Patients with impaired liver function, the elderly, individuals with a history of drug allergies, and those sensitive to Yellow No. 4 (Tartrazine) included in this medication should use it cautiously. While taking this medication, allergic symptoms such as rash, hives, and itching may occur, and if these symptoms appear, use should be discontinued immediately. Changes in blood cell counts, liver function abnormalities, cardiovascular disorders, gastrointestinal symptoms, neurological issues, respiratory problems, muscle and joint pain, and skin adverse reactions may occur, requiring regular testing. If liver function abnormalities occur, use should be discontinued immediately, and appropriate treatment should be sought. Long-term use may increase the risk of osteoporosis and fractures, and hypomagnesemia may occur, so magnesium levels should be checked periodically. This medication suppresses gastric acid secretion, which can increase the risk of bacterial infections in the stomach; therefore, if diarrhea persists, a consultation with a doctor is necessary. Care should be taken when driving or operating machinery as symptoms such as drowsiness may occur. There may be interactions with other drugs, so it is crucial to inform the medical staff about any ongoing medications. It is safest not to use this medication during pregnancy or breastfeeding. The elderly may exhibit adverse reactions due to decreased liver function and should be closely monitored for symptoms. Safety in children has not been established, and there is insufficient experience in usage. In case of overdose, as no specific antidote exists, appropriate treatment and supportive therapy depending on symptoms are necessary. This medication should not be chewed or crushed; it must be swallowed whole and kept out of reach of children. Long-term use may lead to impaired absorption of vitamin B12, so periodic testing is recommended. If symptoms of autoimmune diseases such as erythematosus lupus or systemic lupus erythematosus appear while taking this medication, use should be discontinued immediately, and consultation with a specialist is required. During testing, this medication may raise serum chromogranin A levels, necessitating temporary discontinuation before testing. Kidney issues such as acute interstitial nephritis may occur; if suspicious symptoms arise, use should be discontinued immediately and medical consultation sought.

Serious side effects

Hives, severe swelling, tightness in the chest, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mouth/eye mucous membranes, shortness of breath or difficulty breathing, asthma attack, cough along with respiratory abnormalities, skin or eyes turning yellow (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, vision abnormalities, paralysis, decreased urine output

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechiae

This medication should be stored in a tightly sealed container to protect it from exposure to air or moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance

Pale yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets/PTP×2)