VR Tablet 20/160 Milligrams

Adult dose

Essential hypertension: Take with or without food, preferably at the same time each day (e.g., morning) with 80 mg orally once daily recommended. If blood pressure is not controlled, the dose can be increased to 160 mg daily, up to a maximum of 320 mg. Elderly (75 years and older): Start with 40 mg orally once daily. Renal impairment: For creatinine clearance of 10-20 mL/min, start with 4 mg.

Child dose

The safety and efficacy in children and adolescents under 18 years have not been established, so do not administer.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. Individuals with allergies to this medication, pregnant or potentially pregnant women, and nursing mothers should not take this medication. Patients with severe liver or kidney dysfunction, specific genetic diseases or myopathy should also avoid this medication. Elderly patients, patients with hyperkalemia, and patients with liver impairment should exercise caution when taking this medication and have regular liver function and kidney function tests. This medication can cause muscle pain, muscle weakness, and, rarely, severe muscle damage known as rhabdomyolysis, so consult a physician immediately if you experience muscle pain or weakness. Additionally, since this medication can affect liver function, it should be discontinued and a physician consulted if symptoms of hepatitis or jaundice occur. During treatment with this medication, there may be drug interactions with other medications, so inform healthcare providers about any other medications being taken. Particularly, caution should be exercised when taken with potassium-sparing diuretics or potassium supplements, as this can dangerously elevate potassium levels in the blood. Symptoms such as dizziness or drowsiness may occur while driving or operating machinery, so caution is advised. This medication has not been established for safety or efficacy in children and adolescents, so it is best to avoid its use. In case of overdose, there is a risk of decreased consciousness and low blood pressure, requiring immediate medical attention.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blistering, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress with cough and fever, jaundice, extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis,

Mild side effects

Dyspepsia, nausea, dizziness, headache, constipation, abdominal pain, weakness, conjunctival bleeding, chest pain, nasopharyngitis, urinary tract infection, bruising, increased blood levels of liver aminotransferases (AST, ALT), increased blood creatine phosphokinase, increased plasma potassium, increased gamma-glutamyl transferase, musculoskeletal stiffness, limb pain, impaired sensation, anxiety, upper respiratory infection, pharyngitis, tonsillitis, spinal stenosis,

This medication is sensitive to light; therefore, it should be stored in a container that does not allow light to penetrate. Also, to maintain the drug's effectiveness, it is important to store it at room temperature, between 1 to 30 degrees Celsius.

Appearance

Brown oval film-coated tablets

Package unit

30 tablets (10 tablets/PTP x 3)