Megaglimet Tablet 1/250 mg

Adult dose

This medication is administered 1-2 times daily before meals or with meals. The dosage can be adjusted considering each patient's current therapy, effectiveness, and tolerability, for which appropriate blood glucose monitoring should occur. Generally, treatment is initiated at a low dosage, and the dose can be modified based on the patient's currently taken medications and blood glucose levels. In clinical trials, the initial daily dosage was Glymepiride / Metformin Hydrochloride

This medication may cause severe lactic acidosis or hypoglycemia; therefore, it should be temporarily discontinued and a doctor consulted in the event of rapidly declining kidney function or dehydration symptoms. It should not be used in patients with impaired kidney function or severe liver dysfunction, pregnant or breastfeeding women, or patients with acute metabolic acidosis. In the initial stages of treatment, the risk of hypoglycemia is high, so patients with irregular meal patterns, poor nutritional status, excessive exercise, or alcohol consumption should be particularly cautious. This medication may cause gastrointestinal disturbances (diarrhea, nausea, vomiting, etc.), which are usually temporary; however, if severe symptoms occur, discontinuation may be necessary. Allergic reactions or skin rashes, as well as abnormal blood symptoms may occur; if any unusual symptoms arise, the doctor should be informed immediately. Regular monitoring of kidney function, blood glucose, and hematological tests are required. Monitoring for potential vitamin B12 deficiency is also necessary. There may be interactions when taken with other medications, so inform the healthcare professional of any medicines being taken. Pregnant women or those planning to become pregnant should not take this medication, and breastfeeding women should consult with a doctor. In cases of overdose, severe hypoglycemia or lactic acidosis may occur, so the prescribed dosage must be adhered to, and immediate medical attention should be sought if any unusual symptoms arise. Caution is needed while driving or operating machinery due to the risk of accidents from hypoglycemia or dizziness. The safety and efficacy of this medication have not been established in children, so caution is advised when using it.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/eye mucosa, difficulty breathing or shortness of breath, asthma attack, respiratory issues accompanied by coughing and fever, yellowing of skin or eyes (jaundice), generalized weakness, sudden and severe headaches, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, significantly reduced urine output

Mild side effects

• Nausea
• vomiting
• abdominal bloating
• loss of appetite
• indigestion
• constipation
• abdominal pain
• blood glucose control issues
• headache
• malaise

This medication should be stored in a tightly sealed container to prevent air and moisture exposure. It is also recommended to keep it at room temperature between 1 degree and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness for an extended period.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle