Joah Pamotidine Tablet 20mg

Adult dose

For gastric and duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, Zollinger-Ellison syndrome: 20mg orally, twice a day (after breakfast, after dinner, or at bedtime) or 40mg orally, once a day (at bedtime). Treatment for upper gastrointestinal bleeding should begin with an injection, switching to oral administration once feasible. Improvement in gastric mucosal lesions caused by acute gastritis and acute exacerbation of chronic gastritis.

This medication should not be used in certain patients. For example, it should not be administered to patients with allergies to its ingredients or similar drugs, or those with a genetic problem digesting lactose. Additionally, caution is required in patients with a history of drug allergies, kidney or liver problems, heart disease, and the elderly. Particularly, for patients with decreased kidney function, the drug concentration may increase, necessitating a dosage adjustment. Although rare, serious side effects can appear during the use of this medication. For instance, severe allergic reactions, blood abnormalities, cardiac rhythm problems, liver dysfunction, muscle damage, changes in consciousness, and kidney issues may occur. If such symptoms arise, the medication should be stopped immediately and medical attention sought. Generally, during treatment, it is essential to monitor symptoms and blood, liver, and kidney functions closely, and if this medication is ineffective, it may be better to switch to alternative treatments. This medication dissolves in the mouth but is not absorbed through the oral mucosa, so it should be swallowed with saliva or water. Patients undergoing hemodialysis should be cautious, as the effectiveness may decrease if this medication is used with certain phosphate binders. Moreover, it may interact with other medications, especially when taken with certain antifungals or anticancer drugs. The elderly may be at increased risk of elevated drug concentrations due to decreased kidney function, thus requiring cautious dosage reduction or extended intervals between doses. Women who are pregnant or may become pregnant should only use this medication if its benefits outweigh the risks, and breastfeeding women are advised to discontinue breastfeeding. Safety in children has not been sufficiently established, so caution is advised in their use. Finally, while this medication can be placed on the tongue and dissolved with saliva, it should not be taken lying down without water, as it may mask gastric cancer symptoms, hence should only be used after confirming malignancy.

Serious side effects

Shock, anaphylaxis due to hypersensitivity, respiratory distress, general flushing, angioedema (facial edema, pharyngeal edema, etc.), urticaria, pancytopenia, agranulocytosis, aplastic anemia, hemolytic anemia, thrombocytopenia, Stevens-Johnson syndrome, Lyell's syndrome, liver dysfunction, jaundice, rhabdomyolysis, QT prolongation, ventricular tachycardia (including Torsades de Pointes), ventricular fibrillation, altered consciousness, generalized seizures (tonic, clonic, myoclonic), epilepsy

Mild side effects

• Rash
• urticaria (erythema)
• facial swelling
• leukopenia
• eosinophilia
• constipation
• diarrhea
• dry mouth
• nausea
• vomiting

This medication should be stored in a tightly sealed container to protect it from air and moisture. It should be kept away from direct sunlight and stored at a normal room temperature, avoiding extremes of heat or cold.

Appearance

Green round film-coated tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 300 tablets/bottle