Medication info
Esomeprazole Magnesium Trihydrate 20 mg

Esomeprazole Magnesium Trihydrate 20 mg

Prescription medicationTablet경구 · 정맥
Ingredient · strength
Esomeprazole Magnesium Trihydrate›22.25mg / 1 tablet
Manufacturer / importer
(주)오스코리아제약
Appearance
Light pink round film-coated tablet
Packaging
28 tablets/box [14 tablets/Alu-Alu×2]
Approval status
Active

MFDS item code 202000181 · Approved 2020.01.13

Summary

Main use
Improvement of gastrointestinal diseases such as treatment of gastroesophageal reflux disease (erosive esophagitis) and prevention of recurrence of Helicobacter pylori positive peptic ulcers.
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquids such as water and should not be chewed or crushed. Patients who have difficulty swallowing tablets may disperse this medication in half a cup of still water for ingestion. Other beverages should not be used, as they may dissolve the enteric coating. Stir until the tablet dissolves and drink immediately or within 30 minutes without chewing, and rinse the cup with half a cup of still water and drink it again.
Children's dosage
There is no experience administering this medication to children under 12 years of age.

Ingredients

Manufacturer
(주)오스코리아제약

Efficacy & effects

Improvement of gastrointestinal diseases such as treatment of gastroesophageal reflux disease (erosive esophagitis) and prevention of recurrence of Helicobacter pylori positive peptic ulcers.

  • Gastroesophageal reflux disease
  • erosive esophagitis
  • esophagitis
  • duodenal ulcer
  • peptic ulcer
  • upper gastrointestinal symptoms
  • pain
  • discomfort
  • burning sensation
  • gastric ulcer
  • duodenal ulcer
  • Zollinger-Ellison syndrome
View approved original text

This medication is used for the treatment of gastroesophageal reflux disease, especially erosive esophagitis, and for long-term maintenance therapy to prevent recurrence in patients with esophagitis. It is also effective for symptom relief in patients with gastroesophageal reflux disease without esophagitis. It is used in combination with antibiotics for eradication of Helicobacter pylori, as well as for the treatment and prevention of recurrence in patients with duodenal ulcers and peptic ulcers. It is indicated for the short-term treatment of upper gastrointestinal symptoms due to the use of non-steroidal anti-inflammatory drugs and for patients requiring continuous treatment to prevent gastric and duodenal ulcers. It is also used for the treatment of Zollinger-Ellison syndrome and as maintenance therapy to prevent rebleeding from gastric and duodenal ulcers after intravenous administration. Thus, it is effective in improving various symptoms and complications of gastrointestinal diseases.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. Patients who have difficulty swallowing tablets may disperse this medication in half a cup of still water for ingestion. Other beverages should not be used, as they may dissolve the enteric coating. Stir until the tablet dissolves and drink immediately or within 30 minutes without chewing, and rinse the cup with half a cup of still water and drink it again.

Children's dosage

There is no experience administering this medication to children under 12 years of age.

Precautions

This medication should not be administered to certain patients. For example, patients who are allergic to this medication or any of its components, or have had hypersensitivity reactions, those allergic to penicillin antibiotics or macrolide antibiotics, patients taking certain heart-related medications, breastfeeding women, and patients with a history of myocardial infarction should not use this medication. This medication contains the dye Yellow No. 5, so individuals with allergies or hypersensitivity to this component should use it cautiously. This medication can cause various adverse reactions, so if symptoms such as headache, dizziness, abdominal pain, diarrhea, skin rash, muscle pain, or liver enzyme abnormalities occur, consult a doctor immediately. Serious skin reactions or blood abnormalities, though rare, have also been reported. Regular monitoring is required for long-term use of this medication, and if there are any changes in symptoms while taking the medication, consulting a doctor is essential. This medication has a high potential for drug interactions, so inform healthcare providers of any other medications being taken. Caution is particularly needed when used with antibiotics, antiviral drugs, anticoagulant medications, etc. The safety data for this medication during pregnancy is limited, so individuals who are pregnant or planning to become pregnant should consult with a physician before use. Breastfeeding women are advised not to take this medication, as information about its transmission into breast milk is insufficient. There are no special antidotes for overdose, so if symptoms arise, visit a healthcare facility immediately for appropriate treatment. This medication should be kept out of reach of children and should not be transferred to other containers.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema, anaphylactic reaction, shock, severe hypomagnesemia, jaundice, hepatitis, liver failure, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, Clostridium difficile associated diarrhea, seizures, severe skin reactions (SJS, TEN, DRESS)

Mild side effects

Headache, dizziness, paresthesia, drowsiness, taste disturbance, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal distension, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, increased liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, muscle weakness, interstitial nephritis, gynecomastia, asthenia, increased sweating, Clostridium difficile associated diarrhea, allergic reactions, back pain, chest pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a sealed container. It is recommended to maintain storage temperatures between 1 degree and 30 degrees Celsius for optimal effectiveness.

Appearance and packaging

Appearance

Light pink round film-coated tablet

Package unit

28 tablets/box [14 tablets/Alu-Alu×2]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.