Ducaro Tablet 60/10/20 mg (Pimodipine, Amlodipine, Rosuvastatin)

Adult dose

This medication should be taken once daily, one tablet, with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). The dosage of Pimodipine/Amlodipine combination is titrated according to blood pressure management at 30/5 mg, 30/10 mg, 60/5 mg, and 60/10 mg. Rosuvastatin starts at 5 mg once daily and can be adjusted to 10 mg if necessary.

Child dose

The safety and efficacy in pediatric and adolescent patients under 18 years of age have not been established, hence it is not prescribed.

This medication can cause serious harm to the fetus and newborn if taken during pregnancy, especially in the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. Patients with hypersensitivity to any component of this medication, pregnant women, nursing mothers, patients with severely impaired liver function, and patients with poor kidney function should not take this medication. Patients with low blood volume or salt depletion, those with impaired kidney function, the elderly, and patients with myasthenia gravis should use this medication with caution and must closely monitor their condition while on it. This drug may affect the liver and kidneys, so regular liver and kidney function tests should be done before and during treatment. If symptoms such as muscle pain or weakness, rash, itching, dizziness, nausea, or abdominal discomfort occur, consult a doctor immediately, especially since muscle-related symptoms may indicate serious side effects. This drug may interact with other medications; therefore, patients should inform their healthcare provider if they are taking any other drugs, especially potassium-sparing diuretics, lithium, non-steroidal anti-inflammatory drugs, or certain antibiotics or antifungals. Women of childbearing potential should use appropriate contraceptive methods while taking this drug, and nursing women should either avoid this medication or stop breastfeeding. The safety and efficacy of this medication have not been established in children or adolescents under 18 years of age; therefore, it is not recommended for this population. In case of an overdose, symptoms such as hypotension, arrhythmia, and severe vasodilation may occur; hence, do not exceed the prescribed dose and seek medical attention if adverse effects occur. During treatment, caution is necessary as dizziness may occur while driving or operating machinery. Store this medication in a safe place out of reach of children, and avoid transferring it to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in the oral/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory discomfort with cough+fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizure, confusion, visual disturbances, paralysis, urination

Mild side effects

• Nausea
• peripheral edema
• nasopharyngitis
• influenza
• increase in serum creatine phosphokinase
• dizziness
• essential tremor
• rash
• itching
• dyspepsia

This medication should be stored in a sealed container to protect it from air and moisture, ideally at a temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's efficacy for an extended period.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP*3]