Rovacan Tablets 5mg (Rosuvastatin Calcium)

Adult dosage

The initial dose is once daily 5 mg, and if a greater reduction in LDL cholesterol is needed, the maintenance dose can be adjusted accordingly. The maintenance dose is typically 10 mg once daily, and most patients are controlled at this dosage. The maintenance dose should be adjusted appropriately based on LDL cholesterol levels, therapeutic goals, and the patient's response at intervals of 4 weeks or more, with a maximum increase up to 20 mg per day.

Children's dosage

The usual dosage range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is once daily 5 mg to 20 mg. The dosage should be individualized according to the recommended therapeutic goals for each patient.

This drug should not be used in certain patients. For example, it should not be administered to patients with hypersensitivity to this drug, those with active liver disease, myopathy patients, and those with severe renal impairment. Pregnant or breastfeeding women should not use this drug, and women of childbearing age should use appropriate contraceptive methods. High-dose administration is contraindicated in patients at high risk of muscle-related disorders or those with a history of certain genetic muscle diseases, and these patients should be treated with caution. This drug contains lactose, so patients with lactose intolerance should not take it. Patients who consume excessive amounts of alcohol or have a history of liver disease should undergo regular liver function tests before and during treatment with this drug. If symptoms of muscle pain or weakness occur, inform medical staff immediately and check for muscle damage through blood tests if necessary. Treatment should be discontinued if acute renal failure or severe metabolic disorders occur during the use of this drug. Particularly, elderly patients, those with renal impairment, and patients with hypothyroidism, who are at higher risk of muscle damage, should be closely monitored. This drug may interact with other medications, so inform healthcare staff of any medications currently being taken and discuss dosage adjustments or co-administration. Its safety during pregnancy has not been established, so it should not be used during pregnancy or while breastfeeding. In case of overdose, as there is no specific antidote, immediate medical treatment and monitoring should be obtained. Caution is advised while driving or operating machinery, as dizziness may occur. Rarely, during the use of this drug, serious skin reactions, liver function abnormalities, muscle damage, and other adverse effects may occur; therefore, contact medical staff immediately if abnormal symptoms appear.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough + fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• muscle pain
• weakness
• itching
• rash
• hematuria

This drug should be stored in a tightly closed container, avoiding exposure to air or moisture, and ideally at room temperature between 1 degree and 30 degrees Celsius. This storage ensures the drug's effectiveness and safety.

Appearance

Yellow round film-coated tablets

Package unit

28 tablets (14 tablets/PTP X 2)