Dirosta Tablet 5/20mg

Adult dosage

Dirosta Tablet 5/20mg is administered only to adults, and the dosage should be individualized based on the response to amlodipine and atorvastatin respectively. Amlodipine (S-amlodipine): Administer 5 (2.5) mg orally once daily, and may increase up to 10 (5) mg per day based on patient response. Atorvastatin: For patients with primary hypercholesterolemia and mixed dyslipidemia, 10 mg once daily is the recommended starting dose.

This medication should not be used in certain patients. For example, patients who are allergic to this drug or similar drugs, have severe liver dysfunction, are pregnant or breast-feeding women, or have severe muscle disorders should not use it. Additionally, patients who have recently experienced a myocardial infarction or are in severe hypotensive shock should also avoid this medication. This medication should be used with caution in patients with severely impaired kidney function, the elderly, alcoholics, or those with a history of liver disease. Individuals at high risk of muscle abnormalities should have their muscle enzyme levels checked before starting treatment to ensure careful administration. Generally, this medication is well tolerated, but side effects such as flushing, fatigue, edema, dizziness, headache, and dyspepsia may occur. Muscle pain or symptoms of liver dysfunction may rarely occur, so if any abnormal symptoms appear, it is important to inform healthcare professionals immediately. Women who are pregnant or may become pregnant must ensure appropriate contraception while taking this medication and should stop taking it immediately if pregnancy is confirmed. Breastfeeding women should also avoid taking this medication, and it is recommended to discontinue breastfeeding while on this medication. This medication can interact with many other drugs, so it is crucial to inform healthcare professionals about any concomitant medications. Special caution is needed when co-administering with drugs that are metabolized in the liver or those that can cause muscle toxicity. In cases of overdose, blood pressure may drop excessively or heart rhythms may become abnormal, necessitating immediate medical attention. The safety and efficacy of this medication in children and the elderly have not been sufficiently studied, and it should be used cautiously after consultation with healthcare professionals in these cases. Lastly, this medication should be kept out of the reach of children and should not be transferred to another container.

Serious side effects

• Hives
• severe swelling (edema)
• difficulty breathing
• yellowing of the skin or eyes (jaundice)
• extreme lethargy
• toxic epidermal necrolysis
• severe allergic reaction
• severe liver abnormalities
• hepatitis
• cholestatic jaundice

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is best stored at room temperature between 15 to 30 degrees Celsius.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle