Medication info

Rabiwon Tablet

Prescription medicationTablet경구Approval withdrawn
Ingredient · strength
Tripotassium Bismuth Dicitrate›200mg / 1 tabletRanitidine Hydrochloride›168mg / 1 tabletSucralfate Hydrate›600mg / 1 tablet
Manufacturer / importer
(주)서울제약
Appearance
Light green rectangular film-coated tablet
Packaging
10 tablets/bottle, 30 tablets/bottle, 300 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 201906384 · Approved 2019.09.10

This product's status changed to Approval withdrawn on 2024.02.20. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of gastrointestinal diseases such as gastric and duodenal ulcers and gastritis
Who takes it
Adults
Adult dose
Typically given orally as 1 tablet twice daily, regardless of meals, before breakfast and at bedtime. 1) Gastric and duodenal ulcers Administer 1 tablet twice a day or 2 tablets once a day at bedtime. Particularly for duodenal ulcer patients, administering 2 tablets twice a day before breakfast and at bedtime may achieve a higher cure rate. 2) Gastroesophageal reflux disease For 8 weeks, administer 1 tablet, twice daily, or 2 tablets once at bedtime.

Ingredients

Manufacturer
(주)서울제약

Efficacy & effects

Treatment of gastrointestinal diseases such as gastric and duodenal ulcers and gastritis

  • Gastric ulcer
  • duodenal ulcer
  • gastritis
  • Zollinger-Ellison syndrome
  • gastroesophageal reflux disease
  • Mendelson's syndrome
  • post-surgical ulcer
  • gastric ulcer due to non-steroidal anti-inflammatory drugs
  • duodenal ulcer due to non-steroidal anti-inflammatory drugs
View approved original text

This medication is used to treat ulcers in the stomach and duodenum, gastritis, Zollinger-Ellison syndrome, and gastroesophageal reflux disease. It is also effective for preventing Mendelson's syndrome when administered before anesthesia and for preventing or treating ulcers that may occur post-surgery. It is used to treat gastric and duodenal ulcers caused by non-steroidal anti-inflammatory drugs (NSAIDs). Overall, it helps improve various gastrointestinal disorders.

How to take

Adult dose

Typically given orally as 1 tablet twice daily, regardless of meals, before breakfast and at bedtime. 1) Gastric and duodenal ulcers Administer 1 tablet twice a day or 2 tablets once a day at bedtime. Particularly for duodenal ulcer patients, administering 2 tablets twice a day before breakfast and at bedtime may achieve a higher cure rate. 2) Gastroesophageal reflux disease For 8 weeks, administer 1 tablet, twice daily, or 2 tablets once at bedtime.

Precautions

This medication should not be administered to patients with impaired kidney function or those undergoing dialysis. Patients who have had allergic reactions to this drug or its components should also avoid its use. It should not be given to patients with a history of acute porphyria, as it may worsen symptoms. It is safer to avoid use in patients who have had upper gastrointestinal surgery, in pregnant women or those who may become pregnant, and in premature infants and newborns. Patients on a diet that restricts potassium intake should not take this medication. Caution is advised for patients with impaired liver function, those who have previously had drug hypersensitivity, elderly patients, and patients with kidney problems. Particularly, regular monitoring is necessary when taking this medication along with non-steroidal anti-inflammatory drugs due to the risk of gastrointestinal bleeding. This medication can mask symptoms of gastric cancer, so gastric ulcer patients or middle-aged individuals with recent dyspeptic symptoms should confirm malignancy before treatment. Patients with gastric or duodenal ulcers caused by Helicobacter pylori infection require bacterial eradication therapy. Caution is required for seriously ill patients, those with hypophosphatemia, and dysphagia patients, as the component sucralfate may cause bezoars or respiratory complications. During treatment with this medication, allergic reactions, skin rashes, blood abnormalities, liver function abnormalities, cardiac arrhythmias, gastrointestinal symptoms, and neurological abnormalities may occur. If any unusual symptoms arise, immediate consultation with healthcare professionals is necessary. Long-term use should be avoided and if no therapeutic effect is observed, it is advisable to switch to another medication. Regular blood tests, liver function tests, and kidney function tests should also be performed. Elderly patients, those with chronic lung disease, diabetes, and patients with compromised immunity should be cautious as the risk of developing pneumonia may increase with this medication. If dizziness or drowsiness occurs while taking this medication, driving or operating hazardous machinery should be avoided. There may be interactions with other medications, so especially if taking anticoagulants, antibiotics, or antiepileptics, inform healthcare professionals. Some medications may require spacing during administration, and when used with antacids, proper time intervals should be maintained. It is safest for pregnant or breastfeeding women not to use this medication, and safety in pediatric patients has not been established, so administration is not recommended. In cases of overdose, emergency treatment such as vomiting or gastric lavage may be necessary, and in severe cases, removal through blood dialysis can be considered. This medication may decrease gastric acid secretion, promoting bacterial proliferation in the stomach; therefore, regular check-ups, including eye examinations, are necessary during prolonged use.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema, anaphylactic shock (severe allergic reaction), severe swelling (edema), chest pain, difficulty breathing, respiratory complications, jaundice, hepatitis, severe liver dysfunction, severe skin reactions, severe neurological symptoms (severe headache, seizures, confusion), severe edema, thrombocytopenia, agranulocytosis, pancytopenia, myelosuppression, aplastic anemia, acquired immune hemolytic anemia

Mild side effects

  • Skin rashes
  • angioedema
  • fever
  • bronchospasm
  • hypotension
  • chest pain
  • nausea
  • vomiting
  • constipation
  • diarrhea
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  • abdominal bloating
  • abdominal pain
  • loss of appetite
  • dizziness
  • drowsiness
  • confusion
  • seizures
  • agitation
  • insomnia
  • heaviness
  • malaise
  • anxiety
  • confusion
  • depression
  • hallucinations
  • blurred vision
  • involuntary movement disorders
  • gynecomastia
  • excessive milk secretion
  • erectile dysfunction
  • decreased libido
  • joint pain
  • muscle pain
  • skin itching
  • stomatitis
  • hair loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so storing it in a closed container is important. The storage temperature should be maintained between 1 and 30 degrees Celsius, avoiding direct sunlight and high temperatures.

Appearance and packaging

Appearance

Light green rectangular film-coated tablet

Package unit

10 tablets/bottle, 30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.