Birodi Tablet 2.5 mg (Esamolodipine Besylate Hydrate)

Adult dose

As Esamolodipine, administer 2.5 mg orally once daily, may increase to a maximum of 5 mg per day depending on the patient's response. Take this medication with a sufficient amount of water.

This medication should not be used in certain patients. For example, it should not be administered to individuals who have allergies to this medication or its components, pregnant or breastfeeding women, patients in severe shock, patients with severe heart valve disease, patients with unstable angina, patients who have recently had a myocardial infarction, patients with severe liver dysfunction, patients with severe hypotension, and patients with genetic metabolic disorders such as lactose intolerance. Caution should also be exercised for patients with very poor kidney function, the elderly, patients with acute heart failure, patients with rapidly increasing blood pressure, and patients with mild to moderate liver dysfunction. While taking this medication, various side effects may occur, such as flushing and a sensation of warmth, as well as fatigue, edema, palpitations, dizziness, headache, and indigestion. Rarely, there may be hypotension, skin rash, liver function abnormalities, and allergic reactions, so if symptoms are severe or unusual, consult a healthcare professional immediately. Discontinuing the medication suddenly may worsen symptoms, so dosages should be adjusted gradually under a physician’s guidance when stopping or changing the dose. This medication may interact with other drugs, so inform healthcare providers about any medications currently being taken. Special caution is required when taken with certain antibiotics, antihypertensives, antidepressants, and grapefruit juice. Pregnant or breastfeeding women should avoid using this medication due to uncertain safety, and breastfeeding should be discontinued if using this medication. In children, use is recommended only for those aged 6 years and older, and elderly patients may be more sensitive to the effects and side effects of the medication, so dosing should start at a low dose and administered cautiously. In the event of overdose, severe hypotension, cardiac abnormalities, and coma may occur, requiring immediate emergency treatment; in such cases, aggressive treatment should be carried out according to healthcare providers' instructions. Store the medication out of reach of children and do not transfer it to another container for safety. Finally, this medication is said to not pose a carcinogenic risk or induce genetic abnormalities even with long-term use.

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, angioedema, toxic epidermal necrolysis, severe skin reactions, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and very

Mild side effects

• Flushing with warmth
• fatigue
• edema
• palpitations
• dizziness
• headache
• migraine
• weakness
• abdominal pain
• nausea

This medication can be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is best to maintain a storage temperature at room temperature between 1 to 30 degrees Celsius. This helps to retain the medication's efficacy and safety over time.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle